Global Patient Feedback for Cymbalta (Duloxetine) ( Post a comment )

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Question/Comment:

Does anyone know what the highest dose of Cymbalta you can take? I'm thinking it's 120 mg. but not sure. I"m taking 60 mg. right now.

39 year old Female

Answer/Reply:

I currently take 120 mg - I have not heard of anybody taking a higher dosage than that.

49 year old Female

Question/Comment:

My doctor replaced Lexapro w/ Cymbalta for depression and fibromyalgia. Just started 30 mg. three days ago and feel immediate relief. Have samples to up dosage to 60 mg after a approx. ten days. I am wondering if I should stay at 30 mg. and not go to 60. Have always been hyper sensitive to meds.

62 year old Female

Answer/Reply:

I currently take 30mg of Cymbalta and 40mg of Lexapro daily for depression, anxiety and fibromyalgia. In addition, I am allowed up to 4mg of Ativan throughout the day and an additional 2mg at bedtime. Although this seems like too much medication, I have finally found relief from the sadness and pain associated with these conditions. For me, the addition of Cymbalta to my regimen was key in allowing me to function again.

48 year old Female

Answer/Reply:

I just started cymbalta. I also take ultram, piroxicam, and flexeril (prn) for ankylosing spondylitis and fibromyalgia. It seems to be working good so far, in less pain...but it makes me tired. I went into drug interactions and it's a class 5 with each of these drugs.
Is there something else for anxiet, depression and pain that would work better? And is it really that addictive that you experience painful withdrawls? My dr has told me none of this.

39 year old Female

Answer/Reply:

Being a healthcare professional, my advice, as would be the advice of most other healthcare professionals, only the lowest possible effective dose should be taken of any medication, especially as we get older and even more so for those who are sensitive to medications. Always consult with your doctor about any questions or concerns you may have.

37 year old Female

Answer/Reply:

If your feeling comfortable at that dose you should talk to your doctor about staying at that level. You may have to increase at a later date but you don't have to at this point. The smallest dose of any medication as long as it is effective is the best.

61 year old Female

Answer/Reply:

I also have fibromyalgia, and Lyrica/neuontin doesn't work for me. 20 mg of Cymbalta daily has decreased the muscle pain significantly. I am planning to stay at 20 mg as long as I can - you can always go up later if you need to.

61 year old Female

Question/Comment:

They had me on Cymbalta for over a year. I was on it for depression, anxiety and fibromyalgia. It helped with the depression and anxiety at first but soon I started to getting worse they just kept upping the dose to the highest. Soon I was crying all the time I was a mess and trying to commit suicide. I ended up getting made at my Dr and stopped taking it. with in about 2 weeks I was feeling so much better, I don't cry all the time and cant believe I would even think of suicide. I may still need something but now I'm to gun shy to take anything.

49 year old Female

Question/Comment:

I started Cymbalta about 3 months ago, and despite having to pay $100 a month for it, which I really cannot afford, my husband (who is not very pro-meds!) said, "I will find the money or sell something to keep you on it. You are different. You are happy in the face of extreme circumstances (we have two bipolar ADHD teenagers with many life issues), and I haven't seen you be able to cope with life with your sense of humor back like this in years. Poor guy, he's so normal and our kids our so affected with issues that seem to have skipped a generation and got hit them both hard. My doctor is also trying to get to the bottom of what else I have; I think it is fibromyalgia and I have to say the Cymbalta is not helping with the level of pain I awaken with. I feel like someone beat me with a 2x4 (hands/wrists/elbows/shoulders/hips/knees/feet) when I wake up in the mornings. I wake up in trauma every morning. My mother has RA (to the point of having to have her finger ligaments reattached surgically), Osteoarthritis and fibromyalgia, so I guess it's no surprise I'm inheriting these things; makes life so hard and I definitely find a pain reaction to stress. I also have bulging lumbar discs and a have lived 3.5 years now with an impinged sciatic nerve (43 female).

43 year old Female

Answer/Reply:

cymbalta has been great for my depression - like others I have tryed many antidepressants. I too have a fam. history of rumatiod and osteo., I resently had both overies removed which put me into post men. overnight and my joints were frozen solid in 6 months. I felt like I went to bed at 46 and woke up at 96 yrs old. I stayed on the cymbalta for depression and worked on the joint pain seperatly. My gen. med. Dr. and I have come up with a cocktail that relieves my pain about 80%, 3 - 4 times a month only I start the day with painkillers. I take omega-3, extra D, calcium of course, gloucosimine and most inportant and effective 2 teaspoons of honey everyday! I can really tell if I miss a day. Anyway if cymbalta helps the smile, don't give up on it. A smile helps ease pain too. Good Luck! And good luck to your kids - I have two boys in the autistic spect., it is very difficult physically, emotionally, and romanticly - it gives me goose bumps to hear that your husband noticed your smile!

47yr old female too

47 year old Female

Answer/Reply:

Get your Doctor to prescribe Tramadol 8 a day. Also take one xanax with your cymbalta and you will feel 100% better. Been dealing with the same for 13 years.

59 year old Male

Answer/Reply:

My son was diagnosed with fibromyalgia, and his doctor prescribe Lyrica, which is a medication that affects nerve endings. He told my son that fibromyalgia is a condition which affects the nerve endings.
I took it myself for neuropathy, but didn't notice much difference.
Thought I'd suggest that you look into it.
Also, I take cymbalta for the neuropathy. I notice that there are not significant changes in the neuropathy, but my emotional state seems to be much calmer. (I did not have depression for which it is usually prescribed.) But it also affects the nerves.
I hope this helps you.
Bless you for your ability to raise your children with ADHD. I have a nephew with the same condition. You are truly blessed.

63 year old Male

Answer/Reply:

My doctor just told me about some new information that has come out about fibromyalgia. He said that they have discovered that one of the main aggravaters of the disease is lack of sleep. The deep sleep that most people get every night, someone with fibro doesn't. They are in a light sleep and this prevents the muscle cells from regenerating properly. Maybe you should ask your son's doctor about a good sleep aid.
Marie

45 year old Female

Answer/Reply:

I am 59 years old and I too have used Cymbalta for a long time--it didn;t work as well as expected. I suffer from fibromaygia, osteoarthritis, post-polio syndrome, sjgrogens syndrome, bulging discs, and calcium deposits in my spine. Waking up everyday is a challenge for me too!I feel also like a car hit me!! My doctors keep giving me different meds and trying different things and nothing really works, but I'm still here and taking one day at a time. I hope you get better too! Depression is always there when a doctor says there is not much you can do--even with all the new technology out there. Good Luck!

59 year old Female

Answer/Reply:

I have been on Cymbalta for about 4 years and I understand about not being able to afford it. I take 90 mg. which means a prescription for the 60 mg and another for the 30 mg since they do not make 90 mg. capsules. The price is $100+ for each prescription. I wish Lilly would wise up and take care of this problem. I do believe the Cymbalta does help some with the pain I have from fibromyalgia and it definately has helped me fight major depression. My husband says almost the same thing yours does about my frame of mind. He too declares he will find a way to pay for it. I want to tell you that I have taken 3 shots, about 3 weeks apart of an intravenous therapy called Myers Cocktail and, so far, it has really helped me, especially with the extreme fatigue. Each time I am given a B12 shot before the intravenous cocktail and a potassium pill afterwards and one before I go to bed that night. The cocktail is made up of B vitamins, magnesium and several others that I cannot remember and it is given over a 15 minute period. I find that an ice pack for 15 minutes 3xday helps so much with the sciatic nerve pain in my left lower back, hip and leg. I wish you well.

68 year old Female

Answer/Reply:

You may want to do some research of your own on the 90 mg prescription. My doctor told me the maximum benefit is reached at 60 mgs. After that it is more toxic than helpful.

49 year old Male

Answer/Reply:

I also take 90 mg of Cymbalta daily. But, my doctor prescibed (3) 30mg capsules daily. My insurance has not had a problem with this amount and I just pay one co-pay. I'd check with your doctor, $100 a month difference is huge to me. I also have depression & fibromyalgia, plus I have neurological pain in my back from repeated shingles outbreaks. I also take Lyrica for the fibro. and neuro. pain. I wasn't sure what you were taking the Myers Cocktail for;, was it the fibromyalgia? I am a huge fan of ice packs. I use them on my lower back, my neck and shoulders. Also, I use them on my head (forehead, back of neck or side) for migraines or stress headaches. I do use heat, but only for sinus headaches. I hope this will help with the extra $100. Between all of my prescriptions and my husband's, we buy drugs instead of going out to eat or ever going on vacation. Good Luck!

57 year old Female

Answer/Reply:

First I would like to say see a Rhuematologist. Your story sounds identical to mine 4 years ago. I since have been diagnoised with RA, Fibromyalgia,Degnerative disk disease, and recently AS. I know pain, and there are things the doc can do to help. Along with all of these that you have listed, can be depression. I take Cymbalta, and am very thankful for it now. I did go thru a period of denial and quit taking the meds. What a mistake that was. Now I am back on track and wouldn't change it for anything.

52 year old Female

Answer/Reply:

Have you tried Lyrica for your pain? I take both of these medications for for neuropathy. It's helped me alot since 2006. Before then I felt there was nothing that could help me. From 2000 up until 2006 I was in excruiating pain. Both Cymbalta & Lyrica are fairly new drugs, so for me it wasn't a minute too soon. Pamm 55 year old female

55 year old Female

Answer/Reply:

I have fibro and would like to try Cymbalta. Do you take the Cymbalta and Lyrica together? If so at what dose?

56 year old Female

iGuard.org Answer/Reply:

Cymbalta and Lyrica are sometimes used together. However, using Cymbalta and Lyrica together may increase the risk of excessive sedation. As a result, Cymbalta and Lyrica treatment/dose should be regularly reviewed when these drugs are used together - particularly in elderly or weakened patients. When used together, these medications are usually started at the lowest possible dose and then increased as needed. Talk with your physician about the best dosage combination for you and if the combination would work for your specific condition and symptoms.

Answer/Reply:

Go to a specialist about the RA and fibromyalgia and ask them about the biologics that are out. I have psoriasis which is another condition caused by an over active immune system and have been taking Humira for about 2 years now and am doing great. I had started into the psoriatic arthritis which mimics RA only you don't have the enzyme. When I take my shots on a regular basis I don't hurt and have lots of energy. It's worth checking out.

57 year old Female

Answer/Reply:

Oh my, I totally know about the "freshly beaten feeling" I enjoy it daily. I also have a bi polar 16 year old who has issues that exacerbate the fibro. Unfortunately I can no longer take the Cymbalta-I used to and it was working but, I had to go off for a while and when I tried to get back on it I just couldn't tolerate it-argh! I likely have RA as well so now I am on Plaquenil and I think it is helping but, I keep skipping doses-fibro fog duh. I wish you the best.

38 year old female

38 year old Female

Answer/Reply:

I also take Cymbalta and prozac and a mild muscle relaxer to improve sleep. I personally find that sleeping on a heated mattress pad aids in reducing pain upon waking and then after stretches I move of course not without pain but with less. I have found that Cymbalta really does help with the fibro pain, I ran out a few days ago and could barely make it out of bed. So for sure keep with the med.

63 year old Male

Question/Comment:

I have been taking Cymbalta for 3 years now & it has been wonderful. I was on several different types of antideprsents for 15 years and nothing has helped. My neurologist put me on it for peripheral neuropathy & it had the fantastic effect as an antidepresent. It works great for both reasons & I do not want to get off of it. I have had no side effects from this drug.

49 year old Female

Answer/Reply:

I with the Fibromyalgia was unable turnover in bed .
When I was having this problem I was taking Lyrica
which did nothing for me. When my doctor prescribed
Cymbalta for me then I was able to move about again.
Before then I felt as though someone had a vice grip
on me all the time I was trying to turnover in bed!!
Thanks to Cymbalta I am able to turnover with ease.

56 year old Female

Question/Comment:

I was on Paxil for 30 years, 20mg I loved it, over time my doctor has raised it up. two years ago I noticed my heart rate was elevated to 72 . In the last 3 months Ive been up to 30mg of Paxil and noticed my heart rate was elevated again to 95. This has made me a little nervous , so now the doctor is switching me to cymbalta witch I will try for a couple of weeks and let you know how it works and hopefully it wont elevate my heart rate and the heart will go back to around normal of 65 to 68.

47 year old Male

Answer/Reply:

I have to tell you that I love Cymbalta. I was on Lexapro for several years. I was having many down days where I couldn't tell you the problem.The bad days out numbered the good days I was not able to cry. After switching to Cymbalta my down days were almost eliminated. I know the reason if I am sad. I also can cry when it is appropriate. I started at 30 mg and uppped to 60 mg. I feel any side affects are worth the change in me. My husband was starting to really worry.

50 year old Female

Answer/Reply:

My pain management doctor put me on cymbalta 30 mg each nite for my fibromyalgia pains that were unbearable. The difference was unbelievable and I bless him everyday. The cymbalta has relieve 95% of the pain from my fibromyalgia.

65 year old Female

Answer/Reply:

I believe the Cymbalta will really be a help to you, although I also have a heart rate of around 72. I have been on Cymbalta 60 mg for about a year. Walking daily will help alleviate the heart rate problem; you don't have to walk fast, just a nice, casual walk of 1/2 mile or better. I suffer from fibromyalgia, depression and anxiety. I like the Cymbalta, although taking the alprazolam (Xanax) during the day helps too.

49 year old Male

Answer/Reply:

A heart rate of 72 is normal; the normal range is 60-100.

36 year old Female

Question/Comment:

I was given samples for Cymbalta from my doctor for depression/anxiety. I was told to take 30mg for 1 week and them go up to 60mg. Well the first night that I took Cymbalta which was the 30mg, I woke up in the middle of the night with diarrhea. I first thought it was probably something I had ate or maybe I was coming down with a stomach virus, but the next day I felt terrible! I didn't have any energy whatsoever! I was extremely fatigued and I felt so drowsy! So, I didn't take it anymore, and after it got out of my system I started to feel like myself again. I'm supposed to go back to the doctor in a few weeks. I had been taken wellbutrin xl 300mg, but it wasn't helping me anymore, so that is the reason the changed me over to the Cymbalta. I currently am taking phentermine for weight loss, and I need something that won't counteract with it. Overall I know it had to be the Cymbalta that made me feel that way that day.

29 year old Female

Answer/Reply:

There are SSNRI's and SSRI's, I have tried both types of these drugs and the SSRI's do not work for me at all. Compare the types that your on. Lexapro made feel bah and not carring the Cymbalata I don't even know I am using it. Good luck.

55 year old Female

Answer/Reply:

You might want to ask your doctor if the diarrhea was from not taking the wellbutrin. There are also side effects when you stop taking certain medications also. When I first started taking Cymbalta, it took about 2 weeks for it to work (one week at 30mg, then 60mg after that). I have been on it for 2 years at 60mg and it works wonderful for me. Not everyone is the same though. It has also helped my fibromyalgia, but only when I added Lyrica. I hope this has been helpful.
Marie

45 year old Female

Answer/Reply:

I can't believe you quit taking it after only one day! Almost every medication I've ever taken had one side-effect or another. Read the package insert to get an idea of what to expect and how long it might last. For me, Cymbalta caused nausea, fatigue, dry mouth and dizziness when I stand. All went away within 2 weeks except for the dizziness. Given the great results Cymbalta provides me for the depressive symptoms, I decided that learning to cope with a "head rush" by gettin up slowly and holding on to something until I know I've recovered my equilibrium is well worth it!

I don't know if the Cymbalta is right for you....but giving up on it after one day isn't a fair trial. Did you tell the doctor you were also taking Phentermine?

I hope you find the right med.... it's definitely worth a few minor side effects to feel good again!

56 year old Female

Answer/Reply:

The phentermine has to go, in my opinion. There's a reason is difficult to get a prescription. Its highly addictive. And it would take more than one dosage of cymbalta for you to experience a reaction like that. you probably had food poisoning.

39 year old Female

Answer/Reply:

I love my Cymbalta! I started taking it about 3 years ago and I have had only one extreme depressed state (I was hospilized for one week). The doctor has up'ed my dose to 120 mg per day. If I suffer a side effect I don't know what it is.
When I tried to get another doctor to prescribe me with phentermine she said that if I started taking the medicine it would hurt the effectivness of my anti depressents and mood stabilizer medcines. I would not take them if you are battling depression - got to get your mind straight and then work on the weight. Just my thoughts!

49 year old Female

Answer/Reply:

I started taking Cymbalta about 3 years ago at 30 mg, it was upped to 60 mg later on and I am taking 120 mg. Since starting the medicine I have had only one severe depressed state (hospitalized for one week) and I do not know of any side effects. I expected weight gain due to all of the mood stabilizers and anti-depressents that I take - but with exercise and Weight Watchers I lost over 30 pounds.

A couple of years ago I went to a specialst in weight loss and asked for a prescription of phentermine - she turned me down flat. The doctor said that taking the phentermine along with anti depressents could mess up my current treatments. You need to get your depression under control before you start working on your weight.

Good luck!

49 year old Female

Answer/Reply:

HI I'm a Pharmaceutical Rep not a doctor. But any drug much less an antidepressant you should have def worked with your doctor and given it at least a week not a day. I have been on Cymbalta for over 3 years, with no side affects whatsoever and wanted to post this because you may be scaring potential people that maybe benefited from this drug. One day doesn't equal anything. But that of course is up to a doctor. On a funny note I took wellbutrin and then effexcor and thought I was going to jump out of my skin. Everyone is different! Most of these drugs they don't even know how they really work! They just do.

40 year old Male

Question/Comment:

I am on Sertraline for depression and Cymbalta for Fybromialgia for 3+ years and I am doing great. The reason I chose Cymbalta over Lyrica is that you should not take anti-comvulsives when you don't have convultions.

50 year old Female

Answer/Reply:

I am going to be on Cymbalta for my Fibromyalgia, currently I am on Celebrex, and also Mirapex for my restless leg syndrom what can you all sugest for me to know about with taking these pills?

44 year old Female

iGuard.org Answer/Reply:

Cymbalta is a serotonin-norepinephrine reuptake inhibitor, which means it works on the balancing two of the chemicals in your brain. It takes about six weeks before you will start noticing the effect of the Cymbalta. You may experience side effects before that time. Some of the more commonly reported side effect among iGuard members are: drowsiness, fatigue, dry mouth, weight gain (or loss), dizziness, insomnia and constipation. With Cymbalta it is important to swallow it whole. It can be taken with or without food. Cymbalta and Celebrex may interact. It is important to watch for signs or symptoms of bleeding, such as bleeding gums or bruising easily. Not all patients will experience this interaction, but it is important to watch for it. If you begin to get these symptoms, make sure you call your doctor right away and tell him or her your current medications and symptoms.

Answer/Reply:

I initally was put on Mirapex only for my fibro, since my sleep disorder was supposedly the only cause. But I now take Cymbalta for it & take a tiny dose of mirapex for good sleep. I would say just be aware of how that Mirapex affects you. It helps so much, but if the dose is too high- foro me I appeared to become a complete idiot with my poor memory & concentration. I felt good, but could not remember one thing to the next. I think I was taking 3 mg at the most. I now take .75 for sleep & don't notice any side effects. Also if the Cymbalta is causing digestive problems as it will, that Activia yogurt really did the trick.

46 year old Female

Answer/Reply:

I don't have seizures but have taken take two anti-convulsants for over 20 years- I guess I was on three when I took Lyrica. I still take the anticonvulsants Lamical & Clonezepam for other medical issues- so just wanted to let you know it's okay if Cymbalta become a problem. However for me Cymbalta works better for my fibro than Lyrica. I had more side effects from Lyrica (over eating). Cymbalta just makes to thirsty & some digestive problems which I've dealt with, with probiotics.

46 year old Female

Question/Comment:

I have been on Cymbalta for 18 months now I think, for mild depression and RA pain.
I have had night sweats and more sweating in general, and have an appetite that won't quit! First I thought it was due to a Celiac Sprue diagnoses, and food was being metabolized again with the proper diet, but it hasn't quit! I have gained 40 pounds. Thanks to all your comments, I believe it is the Cymbalta, and am controlling the urge to eat most of the time. My doc just raised my dose to 90mg when I started reading this forum. She said teh methotrexate I take binds with the Cymbalta and prevents its absorption. Thanks for your comments - they are helping me - wish I had something to add to help others.

53 year old Female

Question/Comment:

Cymbalta is my miracle drug! I suffer from Bipolar Disorder (type 2), and it helps with my depression and my anxiety.I take another antidepressant, a mood stabilizer, and anxiety medication. It's my Bipolar "Cocktail" and has worked well for me for years. The only side effect I have with Cymbalta is dry mouth.

43 year old Female

Answer/Reply:

Hi, I am bipolar two and just started back using Cymbalta after I hit the donut hole last June. (Yep it only took 6 months on Cymbalta to hit the hole but the drug was worth it). It is one of the fastest reaction times to get into the system and relieve the depression.....Very little side effects once I am back on them for a few weeks.

63 year old Male

Answer/Reply:

Hello,

I've taken Cymbalta for 9 months now 60mg. its great as long as I don't miss 1 day, if I get busy and don't take that pill, even though as soon as I remember I take it, which sometimes is the next morning, I pay for it, at some time during that next day I experience the moodswings, anxiety, the feeling of pressure and walls closing in on me, I may fly off the handle at someone. Believe me I try not to miss a day but it has happened, I've told my Dr. about this, she says be sure not to miss a day. In my opinion it really didn't seem that bad before taking Cymbalta, I'm 52yr. woman in the menopausal time of my life, I've taken anti-depressants for years from suffering with clinical depression. I'm a little concerned.

53 year old Female

Question/Comment:

i have been taking Cymbalta for three yrs not and it work prefect for me i have major depression and anxiety . for my anxiety i take adavian think that correct but my medciation work great for me.i feel 300% better on this medician than i did with out 90 mgs og cymbalta and 1 mg three time a day for axiety. no more though of harming myself.

46 year old Female

Question/Comment:

I have been on Cymbalta for about 2 years or so. The television ad is great, except for one major thing. It works well for my neuro pain, helps with anxiety and MOOD disorder but NOT for Depression, supposedly it's main thing! I know 6 other people who take 2-60 caps in the a.m. daily for depression and it does not help at all, as with myself. My diagnosis is Major Depression, BPD, ADD, and anxiety/panic. Right now my depression is greatly hindering my growth in other areas-it's BAD! I see my Psych MD monthly and have asked for over 2 months for an additional anti-depressant, as I don't feel Cymbalta is one,but I like it. I heard Prozac CD longlasting once a day 50mg was good, but he says that Cymbalta is enough. I am at my wits end! HELP PLEASE! Also, I get tired in A.M., can Cymbalta be taken P.M.? Judy 54, seems 39

55 year old Female

Answer/Reply:

I was put on Cymbalta about 6 months ago for "pain", by a doctor who saw me once. He through samples at me, I took them and when I decided on a Dr., I told him what I was currently on, so he continued the Cymbalta. After about 2 months I developed bad depression, after 4 months I thought about suicide everyday, and now at 6 months I am going through the Cymbalta Withdraws 10 days now of pure hell. I wasnt aware that you needed to wean off of the drug, and I wasnt aware of the severity of the suicidal idealation. I think Cymbalta is a horrible and misrepresented drug, and if you "Google" Cymbalta withdraw syndrome, yoou might have your Doc take you off perma. Dont want to scare you, just my experience and also have found that thousands of others have had the same prob. Google Cymbalta Bad Reviews, and read for oneself. Hope I helped.

32 year old Male

Question/Comment:

I just weaned off Cymbalta after taking it about 4 years. I was originally put on my my neuro.MD to help me with my tremors, photophobia and migranes.It definately helped.
I was under a doctors care when I have decided to try going off the Medication. I slowly went off mg's, then every other day, etc.
My BIG problem now is my mood swings of depression and almost manic, overwhelming confusion. It is not constant but I have no idea when it will come on.I know Cymbalta is prescribed for depression but it was not my purpose for the drug.
My question is I have been completely off for about 6 weeks. Does it take awhile to get out of my system that these symtoms may go away. I am 50+ and have never experienced these feelings.I really need it to Go awayyyyyy

53 year old Female

Answer/Reply:

I too was put on for similar reasons, and I almost committed suicide, it was all i thought about after awhile, just thought I had depression, kept taking the Cymbalta, but after an accidental dosage skip, I had severe withdraws, so i just quit cold turkey. I had a very bad seizure and several smaller ones, wentt through about 10 days of hell, but now I am feeling alot bettter. If you were taking the generic dulconline or soething like that, then you are going to have longer and worse withdraw symptoms. I read on line @ "Cymbalta Withdraws from Hell.com" or something I googled, and others had complained about symptoms lasting from 1 week to 1 year. Depends, I will never take anothe psych drug again, except for the klonopin i now take for bad anxiety. Hope I helped. Good Luck

32 year old Male

Question/Comment:

Started with 30mg about 6 weeks everything was ok.
Went to 60mg and had the diarreha from hell. doctor kept
telling me it was not the reason (this doesnt happen .)I had various tests
lost weight, blood sugars were wonderful and I felt great other
than the bathroom issue. I felt better.
Went back to 30's and spent my day in bathroom AGAIN

In 2 month time my ekg went from ok to atrial fib?

Listen to your own body you know it best. I am off cymbalta

69 year old Female

Question/Comment:

I would comment that I have recently been placed on Cymbalta. Within a very short time (approximately 2 weeks), I developed a red rash around my eyes, nose and mouth. Also I developed blisters under my eyes. My eyes got so bad that the ends of my eyes cracked and bleed. Around my nose peeled at least 9 times.

Then my migraine neurologist put me on something that sounds like "Efixtor" and I was allergic to that drug with the same type of allergic reaction on my face. Need to say, I am off that drug, also.

58 year old Female

Answer/Reply:

I am a 53 year old female who has been taking Cymbalta for Major Depression with psychotic eposides, I was having anxiety and panic attacks daily, and I am also suffering from Bipolar disorder. I was a mess and did not have control of my life. That was three years ago. I take Cymbalta 60mg in the morning, and Trazadone 100mg hs, and although I still sometimes have my bouts with depression, I now have control over my life and I have been working full-time and attending classes online witha a major in psychology, and I must say that I am doing well. We have to remember that diagnoses are not a predictor of what our lives will be, but they are life's way of telling us that we are not perfect. I am thankful for Cymbalta, and i can live with the side effects that thankfully for me have been minor.

54 year old Female

Answer/Reply:

I am thankful for Cymbalta as well. I did my homework, read the horror stories but took the plung. I also have Bipolar disorder (type 2) thankfully treated well for 20 yrs now with Lamictal. About 4 years ago my Fibro came crashing down on me & within a day I could barely walk- went through the entire battery of tests only to be told nobody treats fibro anymore. Wrong! I found a local doctor through a news story. Put me on increasingly high doses of Mirapex- Sleeptested with PLM- I felt so much better physically, but could barely remember a thing- it was bad & so humiliating. He retired to go into Fibro research. New rhuemotogist put me on Lyrica, also worked well, (my mental facilites came back!) but I could NOT stop eating, gained 15 lbs in 2 months. Despite warnings I gave Cymbalta a whirl. Luckilly I've done extremely well on it. Except when I began I slept literally 3 days. Then when they raised the dose- another sleep-fest. Didn't feel drugged, just couldn't quit sleeping. I stopped the dosage at 40 mg. Still have pain but it's manageable. My chronic fatigue & migraines never changed. Doc put me on Provigal a CNS stimulant which has been a miracle. I make it through the day without drudging through my foggy haze. It's lifted my mood and I'm actually enjoying life like never before. BTW it is also benefical to Bipolar. I'm a walking pharmacy- also taking clonezepam, thyroid meds & Imitrex when he migraines hit. My body's a mess- but it's not going to win. We are all survivors here, justing doing what we can. I'm blessed with health insurance, despite a $1500 RX co-pay which I (happily?) pay just to be able to live a normal (?) life. I would be unbearably miserable without my RX cocktail. Thank you medical advancements, side effects & all.

46 year old Female

Question/Comment:

I have been using Cymbalta, and just about a month ago noticed a bald spot in the back of my head underneath my hair. Since my hair is very thick my daughter had noticed it for me. Would Cymbalta be the cause of this? Also the bald spot has gradually gotten bigger with time in width and length its practically doubled. Not to mention my hair texture is starting to change and my hair is starting to thin. What would be the cause of this?

45 year old Female

Answer/Reply:

Any sudden change in the body can cause hair loss. I would see a doctor about this and make sure it is not something else causing it.

45 year old Female

Answer/Reply:

Have your thyroid checked.

49 year old Female

Question/Comment:

Im almost out of the meds i take but can't aford to go to the doc anymore What should I do???

47 year old Male

Answer/Reply:

Get in touch with the manufacturer. Some offer free meds if you qualify.

68 year old Female

Answer/Reply:

You can go to the Lilly website and print out a request form for you and your doctor to fill out and request a years supply of your cymbalta. Just call your doctors office and ask them to fill out the forms. It shouldn't cost you a visit price. Good luck.

41 year old Female

Answer/Reply:

I've been in the same situation before. I stopped my meds and went into a downward spiral.

I'm sure you're doctor could call you in a refill if you explain the financial situation. Most doctors know stopping a medication suddenly is not good.

You don't mention what you are on but if it's a drug that requires tapering off of then call and talk to your doctor. Maybe they will work something out for you in the meantime until you can afford to see them again. Most doctors have samples they could give you.

45 year old Female

Answer/Reply:

I can't afford my meds either so I went to my doctor and she gave me a form for low income based on what your yearly income is. I get mine free thru AZ&Me Program. Go see her or him and ask them about this program, it has really helped me alot.

55 year old Female

Answer/Reply:

I was in the same position last year. I found Bridges to Access which will give you the meds free for a year as long as your doctor will be your "advocate" and write the script you need and sign the paperwork which, if you have a good relationship with him/her is not a lot of work. Also, I would try my local Health Department. They have sliding fee schedules for appointments to get meds and get counseling. Good Luck to You!

35 year old Female

Answer/Reply:

Just the other day I got a letter from my insurance provider. It was practically begging me to try a brand-new generic drug that is either equivalent to or similar to Cymbalta (I could tell exactly which). I suspect this is quite new. You might want to ask about it. I guess you'd have to go to the doc once more (sorry) but the cost of the meds themselves should go down. Maybe that would help?

The other thing, if you're sure to run out, DO NOT abruptly stop. Instead ration them so you can ease down. I've heard anecdotes and more importantly my doctor has told me that the side effects can be awful stopping abruptly but if you wean yourself off they shouldn't be as bad.

38 year old Female

Answer/Reply:

Most drug companies have programs to supply drugs free or reduced cost to people who can't afford them, check with them. In my area we have a clinic at reduced or no charge for patients who cannot afford the doctor. Check in your city for what is available.

68 year old Female

Question/Comment:

Have any of you had weight gain or loss with Cymbalta?

39 year old Female

Answer/Reply:

yes! 40 pounds.

42 year old Female

Answer/Reply:

I have been slowly creeping up in my weight..approx. 5 lbs.

48 year old Female

Answer/Reply:

I have had weight gain with Cymbalta. I have gained about 30 pounds since being on the drug (3 years). I cannot say with certainty that all my weight gain is due to the drug, but I know it has certainly been hard to lose weight while taking it. It is very discouraging to me.

48 year old Female

Answer/Reply:

I experienced weight loss after being put on Cymbalta. I have been taking it about 3 years now and have never experienced weight gain from the med. I am female, 34 years old.

35 year old Female

Answer/Reply:

I would say no. I have had a loss of 8 pounds between my last two doctor visits, but they have been spaced well apart and I can't attribute it to Cymbalta. I have been taking it for probably two years.

56 year old Male

Answer/Reply:

At first I lost a few pounds but now I have gained that back plus a few xtra.

72 year old Female

Answer/Reply:

I have gained about 16 lbs. with it.

37 year old Female

Answer/Reply:

I have been on Cymbalta for over 3 years and I have gained weight and that does not help with my depression.

49 year old Female

Answer/Reply:

I have gained weight but don't know if it is the Cymbalta or Seroquel that I take.

55 year old Female

Answer/Reply:

gain a lot of weight from the cymbalta [60pds.] and can't get it off also been on it for a long time female from cranston,ri

50 year old Female

Answer/Reply:

I have had weight gain. No matter what I do I can't seem to lose it.

35 year old Female

Answer/Reply:

I originally had a slight weight loss. On maintenance, no real difference. I'm only on 60mg per day. I had higher doses, but settled with 60mg. I gained with Zoloft and never really lost that. Good luck.

42 year old Female

Answer/Reply:

Yes,

I do find my hunger has increased tremendously. I have started gaining weight. Have you read where this medicine is linked to weight gain?

42 year old Female

Answer/Reply:

I started taking 60mg Cymbalta daily about two years ago and was overweight when I started. I did not gain any weight, nor did I lose any. I started a weight loss program this January '09 and have been able to successfully lose 30lbs so far while still taking the Cymbalta so it seems to have not had any effect on my metabolism whatsoever.

39 year old Female

Answer/Reply:

I have gained about 15 pounds over the past 2 years since I started taking the medication.

44 year old Female

Answer/Reply:

Hi,
I've probably gained 8 pounds in the 14 months I've been taking Cymbalta. I seem to have more of a sweet tooth than before and less interest in doing anything I don't find enjoyable.
LB

62 year old Female

Answer/Reply:

Yes, I have gained weight since starting Cymbalta last year in July 2008. The medication really helps my condition but the extra weight I'm not pleased, so I got to work on my weight.

54 year old Female

Answer/Reply:

41 year old female.
YES! I have gained weight from the Cymbalta.

41 year old Female

Answer/Reply:

Gained weight with it. Stopped it for that reason

58 year old Female

Answer/Reply:

ALL MEDICINES HAVE SIDE EFFECTS!. READ THE WARNINGS ABOUT THEM. WHAT THE DRUG MAY CAUSE AND WHAT IT MAY DO.I TOOK CYMBALTA OVER 4 YEARS, STAYED BLOATED GAS NERVOUSNESS ALL THAT. I CANT AFFORD IT ANY MORE, I HAVE NO JOB NO INSURANCE, SO I'AM DOING GOOD WITHOUT IT.THE BEST FORM OF MEDICINE I HAVE EVER FOUND IS JESUS!!!. 44 YEAR OLD FEMALE...

45 year old Female

Answer/Reply:

I have\n't noticed a weight gain yet. Have been on Cymbalta for only a month.

58 year old Female

Answer/Reply:

I have been on Cymbalta for three years now. When I first started I lost six pounds. Since then my weight has been gradually going up. It dose not matter how active or what diet I try I seem not to be able to loss weight. I never thought it was the Cymbalta until I read others comments. I was 165 I now weigh 213.

54 year old female

55 year old Female

Answer/Reply:

Yes , I have gained 20 lbs.

39 year old Female

Answer/Reply:

I have gained weight. I am at my heaviest ever and have not changed my eating habits or exercise for many years. I've been trying to figure out why the gain, but never thought it would be Cymbalta. I guess it makes sense, since that's the only thing different going on with me.

46 year old female

48 year old Female

Answer/Reply:

I have been on cymbalta for a few years. I gained weight at first. Then I started working in a factory and lost weight. When I got let go I gained about 70 pounds. I recently lost 10 pounds but it was VERY hard and feel that I may be gaining a few pounds back. I agree, it does NOT help depression when gaining weight. I may ask to be put on something different. I am at risk because I now weigh 240 pounds and I also smoke.

51 year old Female

Answer/Reply:

no 46 year old female I've stayed the same

48 year old Female

Answer/Reply:

I really didn't have either. It did help with the constant dull pain I feel every day. Sadly I am facing disability retirement soon and decided to do the 60 mile drive to Seattle to the Doctors at the VA. since I am a diabled veteran. I just used my insurance because going to the VA turns into a ALL DAY event when you need to see a doctor. I had my first appointment and found out they don't have Cymbalta and have been on it for years and it seemed to be the only one that really helped me. I either have to find something else through the VA or continue it through a civilian Dr. hopefully I can push getting it on the list for women in the VA. It sure has helped me.

48 year old Female

Answer/Reply:

When was the last time you checked for Cymbalta with the VA? I used Cymbalta from the VA in Dayton, Oh for over 3 yrs until the long term effects of weight, tiredness, etc got to be too much. Sometimes the VA Doctors only know the generic name for the meds, ALL meds are listed by generic name, even if you get one and peel the label and see the NAME BRAND underneath, the sticker will still have it listed with generic name. Try asking for the generic name...cause I KNOW for a FACT that they do carry it although they don't call it cymbalta.

57 year old Male

Answer/Reply:

I have gained 45 pounds since I have been on Cymbalta. This drug has helped me so much. I take it for back pain and nerve damage. I take 30mg twice a day. I did try to cut back to try to 30mg and perhaps just get off of it because of this horrible weight gain, but I felt pain come back right away. So here I am on this drug helping my pain but making me gain weight.

50 year old Female

Answer/Reply:

Yes I gain 20 lbs mi first year taking Cymbalta

47 year old Female

Answer/Reply:

I've been on Cymbalta for approximately 3 years. During that time I have lost a grand-total of 103 lbs with very little conscious effort. Now...can I say that it's because of the Cymbalta and only the cymbalta...no, I can't. But it is what it is - the weight started coming off shortly after starting the medication.

45 year old Female

Answer/Reply:

I TOOK CYMBALTA FOR ABOUT A YEAR, ALL I WANTED TO DO WAS SLEEP AND EAT.
THATS WHEN I PUT ON ABOUT 30 POUNDS. I TOOK IT UPON MYSELF AND GOT OFF THESE PILLS. I KNOW IT WAS THE PILLS, I NEVER HAD THIS PROBLEM BEFORE WITH
WEIGHT GAIN. PS I WAS GIVEN THIS PILL FOR HOT FLASHES OF ALL THINGS.

52 year old Female

Question/Comment:

VERY GOOD IDEA!!! Always research because it is YOUR body and you know best for yourself and afterall it is the "PRACTICE" of medicine "NOT" the "perfection" of medicine! rememeber...Most of those Doctors are "trying" to help us just as bad as we are suffering ourselves;(

44 year old Female

Answer/Reply:

Nexium can break down the coating of cymbalta too quickly, i had the worst panic attack i had ever experienced and i was anxious for 3 weeks following taking both at the same time. benadryl helped slightly and calmed some of my body's uncontrollable shaking. It scares me to this day - something similar but less severe happened to me when i was given haldol while i was taking nexium

22 year old Female

Answer/Reply:

As a fibromyalgia, and HEPC patient, my primary dr, put me on Cymbalta to begin with, suggested I try Lyrica to see if it helped with the fibro,,,I explained to him, that my chiropractor
had suggested some extra enxymes for my gastro problems, he looked at the bottle, and replied, Well, you don't know how much damaged this could do to your liver, with which I replied,,,,,and Cymbalta w/Lyrica WON'T?


51 yr old female

51 year old Female

Question/Comment:

When I try to get off of Cymbalta I experience stomach flu symptoms and headaches out of this world. I am extremely dizzy and weak. How can I get off of this medicine without these symptoms? When I am on it, I am spacey, short memory, vaginal dryness, and if I don't take it the exact time every day, then it makes me sick. Please help!

31 year old Female

Answer/Reply:

Never just quit a medicine like Cymbalta. Step down gradually. Take it every day for a week, then every other day and so on until you can get off of it completely. It may be that you are on too high a dose and that when you lower it you see that you feel better.

47 year old Female

iGuard.org Answer/Reply:

Stopping Cymbalta may cause headache, dizziness, nausea and other symptoms. Cymbalta should not be stopped without discussing with your doctor. If you and your doctor decide to stop the medication, it may be a good idea to decrease the dose slowly to minimize the side effects.

Answer/Reply:

I have tried 2 times to get off this med. My Dr. had me slowly lower the dose over a 3 week period. I had terrible withdrawl symtoms & had to start taking it again.One of the reasons I wanted to get off of it was the price. Is there a similar med out there at a reasonable cost?

47 year old Female

Answer/Reply:

I took cymbalta for three years and never could stop taking it even when the dose was lowered enough to get off of it completely.

I finally went to a doctor that put me on zoloft and I never experiences any withdrawals from not taking the cymbalta. It was a relief to be off of the cymbalta because the price is very high. Zoloft is much lower and works much better in my opinion.

45 year old Female

Question/Comment:

I took Cymbalta for nerve pain for about three months, going from 30mg. to 60mg. My blood pressure went very high and I knew it was the Cymbalta doing that, called my doctor and he said to stop it right away, which I did. Knowing a person should not just stop this medication. my doctor explained that if you were admitted to the hospital and your throat were swollen your medicine would be stopped. It has been two weeks now and I have brain zaps that actually hurt, anything loud hurts my left ear, most scary was I think I had a seizure during the night. This medicine was the only one that helped my nerve pain, but I really think this medicine will be found to be dangerous in the long run. Patients who have been on Cymbalta for a long time must be careful. if they decide to stop this medicine.

71 year old Female

Question/Comment:

I am a 28 year old female and have been on Cymbalta at 120mg since 2005. It was first perscibed to me to help with my Depression and Anxiety/Panic disorder. Since then, it has also helped with my fibromylagia pain as well. The only main side effect I have with this drug is the sleepiness. I now take my medication at night and it helps a little. Other then that, I have no other side effects and am very happy with this medication. I have also been able to loose weight while taking this drug. Recently, Cymbalta has been approved for the foot pain that Diabetics experience. My mom has type 2 diabetes and has suffered from severe foot pain for many years. She has taken several types of medication but none seem to help. I told her about Cymbalta and she gave it a try. Her doctor started her out on just 30mg. After 1 week of usage she saw a HUGE difference in her feet pain. She was very pleased with the results and grateful for the medication. But, now after 2 weeks of taking the drug (with no increase in medication) she has been suffering from a severe rash over her trunk of her body. I never suffered from this side effect and was wondering if anybody else does??? The rash got so bad, she stopped taking Cymbalta. The rash is now gone but her foot pain has returned with a vegence. :( If anyone has any information on Cymbalta and rashes, please reply with your stories and advice. I hate to see my mom suffer and feel responsible for telling her about Cymbalta. She is devastated that something actually helped with her foot pain after 10 years of searching but can't take it because of a horrible rash! Please help!

29 year old Female

Answer/Reply:

Tell her to talk to her doctor about Lyrica. I have peripheral neuropathy too, and experienced tremendous relief when I started taking Lyrica. Naturally these things work great for some people, ok for others, not at all for still others. But you can try it. I also take Cymbalta but I found that Cymbalta does little for the neuropathy in my feet and legs.

57 year old Male

Answer/Reply:

I. too, take Cymbalta for bi-polar depression. I have no foot pain but chopped garlic swallowed with plain yogurt helps keep down the infection in my large, left toenail. I believe I would have diabetes or some other ailments if I did not keep taking garlic. I feel that Cymbalta is safe enough. After all, I've been taking it for about two years now, and I've had no reactions to it. I'm not one to enjoy taking medicine but I really need it if I don't want to go into another "episode" of depression or mania. All medications have risks of side effects but if you are working to rebuild your physcial health and taking some natural cures, then you can also take your medicines!

57 year old Female

Question/Comment:

I have been on cymbalta for 7 months and it has caused severe mood swings I can get very violent at times I have a clean record up until jan of 09 somebody tell me there is someone else out there with the same problems

33 year old Female

Answer/Reply:

What is your dosage? I have been on it for about two years because Lexipro quit working. I am taking 60 mg/day, but have been as high as 90 mg/day. It allows me to function (work, etc.) Prior to that I was extremely withdrawn.

56 year old Male

Answer/Reply:

what ever you do don't stop taking it, your side effects will subside. you might need a stronger dose, i started out on 30mg i am now on 60mg, i can definetly tell the difference. i wasn't able to get mine refilled for at least a week and i can tell the difference when i dont take them, everything got under my skin yesterday or all i did was cry, so keep taking them and maybe get a higher dosage from your doctor it will help you. god bless you and good luck

47 year old Female

Question/Comment:

I have been on Cymbalta for about 1 year. Recently i was raised from 60 mg/day to 120. I was also put on 300 mg/day Lyrica. I take Xanax ( 3 years) The Lyrica and Cymbalta are so expensive I did not fill my February dose. In December I was driving from GA to NC. I was driving all over the road (it is a wonder I was not killed). I wrecked my car almost home and only knew it after it happened. Then I thought things happened (people coming over etc) which did not happen. Is this related to the anti-depressants. I have cried for a month while not taking the Cymbalta so I went back onn 60 mg/day today.

57 year old Female

Answer/Reply:

ALWAYS research things yourself before willingly accepting your doctors decision to up your meds or add/change medications. YOU know more about your body than he does. Yes s/he went to medical school, but other than what you tell him, he doesn't know what is going on inside you. ALWAYS research these things yourself. What I normally do is accept the prescription and then go home and look it up and the possible interactions, side effects and so on before having it filled.

37 year old Female

Answer/Reply:

I am also on Cymbalta and had my dosage upped..I didn't realize you could still be depressed on a smaller dose.. I took Lyrica years ago and it immediately was a side effect nightmare.. Most commercials that have lots of warnings about a new drug may be just that! A warning drug! It also says about Lyrica that you shouldn't take if you have or have had a problem with alcohol.. It doesn't necessarily mean you drink it... It just means that you may be prone to more problems if you have that problem even in your family.. The combination of some drugs or drugs react differently to differently people.. I ran out of my Cymbalta a couple of times and I was a freaking nervous wreck.. Try the Prescription Drug Plan.. It helps people that can't afford meds.. It is dangerous (VERY MUCH SO) to stop taking some meds cold turkey.. I had to go to the emergency room to get some.. Most bigger cities have a hospital that takes in patients for free.. I feel for you.. Been there ; Done that! Hope you feel better soon! A friend!

50 year old Female

Question/Comment:

I was placed on Cymbalta while going through menopause because my doctor did not believe in using hormone replacement therapy. It was supposed to help my hot flashes, sleeplessness, and anxiety. It made me feel like a pleasant zombie, and really affected my memory! I thought I was getting Alzheimer's because I literally couldn't think. I switched to a different gynecologist, who discontinued the Cymbalta and placed me on the lowest dose of HRT possible. Finally, I am myself again! My memory and energy have returned.

46 year old Female

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