Get Informed: Lotrel
Active Ingredient(s)
Amlodipine with Benazepril Hydrochloride
What does it do?
This product is used in the treatment of high blood pressure. It contains a calcium channel blocker (amlodipine) and an ACE inhibitor (benazepril).
- Last Text Update:
- 2009-Nov-21 1:17 AM
- Last Data Update:
- 2009-Nov-20 6:53 PM
Other Names
- Lotrel
- Amlodipine with Benazepril Hydrochloride
How Safe Is It?
- Your Risk Rating
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- Average Risk Rating
-
- Pregnancy Category:
- D
Black Box Warning
This product has a black box warning relating to its risks in pregnancy.
Facts & Figures
- Date Approved
- 03 Mar 1995
- Est US Patients*
- 1,197,000
- Generic Available
- Yes
- OTC Available
- No
User Age Distribution*
< 21
21-39
40-59
60+
Age (Years)
* Estimated number of US people currently taking Lotrel or its active ingredient based on population adjusted patient numbers registered with iGuard.org.
Recent alerts for Lotrel
There have been no alerts regarding Lotrel during the past year.
Lotrel Safety Report
Learn more about iGuard's risk ratings
- Please login or register (it's free) so iGuard can check how Lotrel interacts with other drugs and diseases in your profile.
What is Lotrel used for?
iGuard.org is currently tracking more than 7,000 patients that use Lotrel (or similar drugs with the same active ingredient(s)). Use the table below to learn why iGuard users take this product; click on any underlined condition to get information on other medications used for treatment.
| Disease / Condition | % | Average Severity |
|---|---|---|
| High Blood Pressure | 97% | 
|
| Other | 3% |
|
How well does Lotrel work?
iGuard.org regularly polls our more than 7,000 users taking Lotrel (or similar drugs with the same active ingredient(s)) using the Treatment Satisfaction Questionnaire for Medications (TSQM) . This feedback is continuously updated in tables below for the benefit of the iGuard community. To request scores for specific patient subgroups, please contact research@iguard.org.
Average Satisfaction Score
(out of 10)
Average Effectiveness Score
(out of 10)
- 100%
- of patients are confident that the good things about Lotrel outweigh the bad things.
- 8%
- of patients wish they were told more before they started taking Lotrel.
Common Side Effects of Lotrel
iGuard.org regularly polls our more than 7,000 users taking Lotrel (or similar drugs with the same active ingredient(s)) to monitor the development and frequency of side-effects. This feedback is continuously updated in tables and graphs below for the benefit of the iGuard community.
23% of patients experience side-effects on Lotrel
2% of patients experience signifcant side-effects on Lotrel
Most Common Side Effects...
-
Dizziness
-
Drowsiness
-
Headache
-
Cough
-
Constipation
-
Muscle Pain/Stiffness
-
Hot Flushes
-
Fatigue
-
= 10%
Global Patient Feedback for Lotrel (Amlodipine with Benazepril Hydrochloride) ( Post a comment )
Question/Comment:
I am on Lotrel 10-20mg and geodon 120mg, paxil cr 25mg, topomax 20mg, diovan 160/25mg.....are there any known drug interactions with Low Dose Naltrexone? I am 57 yr old male
Thanks
57 year old Male
Posted: 2009-10-07 20:11:25
iGuard.org Answer/Reply:
There are no drug interactions between Naltrexone and Geodon, Paxil, Topamax, or Diovan listed in the iGuard drug interaction database. However, there is a potential interaction between Naltrexone and Benzapril, one of the ingredients in Lotrel. Using Benazepril and Naltrexone together may significantly increase the risk of liver problems. As a result, the use of these drugs together is normally avoided. It is best to discuss the addition or use of this medication with your physician who has your complete medical history and medication list. You may find that the benefits of the medication will outweigh the possible risks.
Posted: 2009-11-05 01:54:17
Question/Comment:
Will Lotrel cause swelling in thr legs, aankles and feet?
64 year old Male
Posted: 2009-08-01 19:57:52
iGuard.org Answer/Reply:
Some of the most common side effects of Lotrel include swelling of the feet, legs and ankles. If the swelling worsens or persists you should contact your doctor to discuss. In addition if you experience swelling of your face, tongue, throat, or neck you should immediately report that to your doctor.
Posted: 2009-08-06 22:43:38
Answer/Reply:
I was prescribed Lotrel 5-20 after getting no help from Inderal. It worked like a charm, even now after 3 yrs. But whenever I take a pain pill like Vicodin or oxycodone my left foot starts to swell towards the end of the Rx. I don't know what other meds you're taking, but I doubt it's the Lotrel.
47 year old Female
Posted: 2009-08-18 14:15:04
Answer/Reply:
Both my Wife and I take it and have no problems with swelling.
56 year old Male
Posted: 2009-08-19 19:32:58
Answer/Reply:
It may, but when I do my jogging all swelling will disappear---Does for me anyway--Good Luck
70 year old Male
Posted: 2009-08-20 15:21:41
Answer/Reply:
YES, IT'S NORMAL. IT WAS TOLD TO ME BY MY DOCTOR.
38 year old Male
Posted: 2009-08-25 22:19:07
Question/Comment:
I am a 53 yr . old female, I take alot of vitamin supplements,can they interfere with the lotrel?
53 year old Female
Posted: 2009-07-06 21:48:15
iGuard.org Answer/Reply:
There are known drug interactions with many herbal supplements and vitamins. In addition there are several that can elevate or lower blood pressure levels. Your physician as well as your pharmacist should have a complete listing of any medication you are on to make the best assessment for your condition.
Posted: 2009-07-07 14:49:26
Question/Comment:
74 year old male
Can Saw Palmetto be safely taken with Lotrel and Zocor?
75 year old Male
Posted: 2009-07-06 09:50:16
iGuard.org Answer/Reply:
There are no documented studies showing a drug interaction between saw palmetto and Lotrel and or Zocor. However, this does not mean an interaction does not exist - herbal supplements interactions with prescription medications are not well studied. You should notify your doctor that you have started taking saw palmetto and continue with your regular blood pressure and cholesterol monitoring under your doctor's care.
Posted: 2009-07-07 15:20:11
Question/Comment:
DOES THIS MEDICATION CAUSE BACK PAIN IN PATIENTS???????
61 year old Male
Posted: 2009-06-26 20:42:43
iGuard.org Answer/Reply:
Back pain has been reported by patients who take amlodipine with benazepril but it is not a common side effect. iGuard has received some reports of muscle stiffness - Less than 1% of iGuard members report muscle stiffness as a side effect of amlodipine with benazepril. If your back continues to bother you or becomes worse, please contact your physician for a thorough examination into the cause of the pain.
Posted: 2009-06-29 10:20:37
You may post comments for the benefit of other patients or post questions other patients might be able to answer. Comments are submitted for possible publication on the condition that they may be edited. Only your age and gender will be published with your comment, although your other user details will be securely recorded for verification purposes.
Comments may be either questions or answers to previously posted questions. Any iGuard.org user may post questions and reply.
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Patient Comments about
Lotrel