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Get Informed: Hydrochlorothiazide

HYDROCHLOROTHIAZIDE Safety Report

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The average iGuard risk rating for Hydrochlorothiazide is blue . It means that Hydrochlorothiazide normally has a low risk of serious or long-term side effects if used under normal medical supervision.

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What is HYDROCHLOROTHIAZIDE used for?

iGuard.org is currently tracking more than 20,150 patients who are using Hydrochlorothiazide for the following reasons:

DISEASE / CONDITION % AVERAGE SEVERITY
HIGH BLOOD PRESSURE 81%
EDEMA (FLUID RETENTION) 13%
HEART FAILURE/EDEMA 2%
HEART DISEASE PREVENTION 2%
KIDNEY STONES 1%
OTHER 1%  

How well does HYDROCHLOROTHIAZIDE work?

iGuard.org regularly polls our more than 20,150 users taking Hydrochlorothiazide using the Treatment Satisfaction Questionnaire for Medications (TSQM). This feedback is continuously updated in tables below for the benefit of the iGuard community. To request scores for specific patient subgroups, please contact research@iguard.org.

Average Satisfaction Score
(out of 10)
63 %
Average Effectiveness Score
(out of 10)
66 %
75%   of patients are confident that the good things about Hydrochlorothiazide outweigh the bad things.
17%   of patients wish they were told more before they started taking Hydrochlorothiazide.

Common Side Effects of HYDROCHLOROTHIAZIDE

iGuard.org regularly polls our more than 20,150 users taking Hydrochlorothiazide to monitor the development and frequency of side-effects. This feedback is continuously updated in tables and graphs below for the benefit of the iGuard community.

29%
29% of patients experience side-effects on Hydrochlorothiazide
3%
3% of patients experience SIGNIFICANT side-effects on Hydrochlorothiazide
MOST COMMON SIDE EFFECTS
FREQUENT URINATION
= 10%
LESS THAN 1%: BLADDER/URINARY PROBLEMS, DIZZINESS, FATIGUE, ELECTROLYTE PROBLEMS, SEXUAL PROBLEMS, NAUSEA, DROWSINESS, TREMOR, MUSCLE SPASMS, COUGH, ANXIETY, RESTLESSNESS, HAIR LOSS, BLURRED VISION, LOW BLOOD PRESSURE, DRYNESS, THIRST, HEADACHE, CONSTIPATION, HEAVY PERIODS, DRY MOUTH, MUSCLE PAIN, ELEVATED GLUCOSE.

39
Patient Comments about
Hydrochlorothiazide HERE

ACTIVE INGREDIENT(S)
Hydrochlorothiazide
WHAT DOES IT DO?
photo

This product is primarily used for the treatment of high blood pressure. It increases excretion of sodium and chloride by the kidney, although the exact mechanism of its anti-hypertensive effect is not well understood.

Last Text Update: November 20, 2008
Last Data Update: July 3, 2009


OTHER NAMES
  • Hydrochlorothiazide
  • Esidrix
  • Hydrazide
  • HCT
  • Microzide
  • Hctz
HOW SAFE IS IT?
Your Risk Rating: LOG IN
Average Risk Rating
Pregnancy Category B
Black Box Warning No

FACTS & FIGURES
Date Approved 12 Feb 1959
Est US Patients* 3,000,000
Generic Available YES
OTC Available NO
*Estimated number of US people currently taking Hydrochlorothiazide based on population adjusted patient numbers registered with iGuard.org.

Recent HYDROCHLOROTHIAZIDE Alerts

There have been no safety alerts issued for Hydrochlorothiazide in the past year.

Drug Comments for Hydrochlorothiazide (Hydrochlorothiazide)
 

Comments, Questions, and Answers Show Newest | Oldest First 

Question/Comment:

After taking HCTZ for 4 days my BP has increased a little and I have a mild dull headache.

55 year old female
Posted: 2009-06-30 10:49:17     Rating: Star Star Star Star Star

Question/Comment:

Does HCT cause diabetes?

55 year old female
Posted: 2009-06-03 18:16:58     Rating: Star Star Star Star Star

Answer/Reply from iGuard:

Elevated blood glucose, one of the signs of diabetes, is reported by less than 1% of iGuard members taking hydrochlorothiazide. Although some studies suggest that hydrochlorothiazide may increase blood glucose, there are many things that cause a patient to develop diabetes.

Hydrochlorothiazide is often prescribed to diabetics. In fact, the American Diabetes Association recommends that hydrochlorothiazide be used in certain diabetic patients who are having trouble controlling their blood pressure. If you are concerned about hydrochlorothiazide and/or diabetes, please make an appointment with your physician to discuss your concerns.

Posted: 2009-06-05 16:33:14    

Answer/Reply:

No. There are several different types of diabetes. HCT/HCTZ (same drug), Hydrochlorothiazide is a water pill that helps the body get rid of excess build up water in the body system. Everyone should drink plenty of water. If they do not, then the body is tricked into thinking there is not enough water in the system so it starts building up as storage in the body to prevent dehydration for temporary prevention of dehydration. If still not enough drinking water, then the body goes into storage of fluids and then the pockets of water can be found in fatty tissue. swelling, etc. This then can get into high blood pressure Hypertension, kidney disease, heart disease, etc. and other diagnosis that needs to be treated by your physician. Joy

71 year old female
Posted: 2009-06-14 15:50:53     Rating: Star Star Star Star Star

Question/Comment:

I have taken Hctz for years for blood pressure. In the past 6 months, my feet hurt constantly. I have bought 4 different pairs of walking shoes, nothing helps. I have been on statins for cholestrol, have stopped taking them, to see if symptoms deminish. Symtoms still there. The foot pain is bilateral and in the proximal 1st and 2nd metatarsal bone. Could this be gout?

51 year old female
Posted: 2009-05-08 13:05:18     Rating: Star Star Star Star Star

Answer/Reply:

Could be lack of minerals due to the "washing" effect of the Hctz. One may need to rethink what they eat and add more green and red vegetables or a mineral tablet. I have taken Hctz for many years, but I also take vitamins and minerals. Occasionally I get a cramp in a muscle but not too often. Most of the cramps come in a leg where I have bursitis, and a foot (same leg) that was broken about 45 years ago.

75 year old female
Posted: 2009-05-12 15:20:36     Rating: Star Star Star Star Star

Answer/Reply:

it could also be a lack of potassium in your muscles from the hctz. you need to ask your dr. about prescribing a potassium pill and to have a blood test to test your potassium level. lack of potassium will give you mild to severe muscle cramps.

48 year old female
Posted: 2009-05-24 03:10:58     Rating: Star Star Star Star Star

Answer/Reply:

If you have a history of gout, taking Htcz could cause problems. This is more so if you are taking any of the blood pressure meds such as lisinopril. They have a history of causing gout or gout symptoms. I have had the gout for the past 21 years and both of the above medications required an adjustment in my medications to deal with the gout. Even wth the adjustments, I will get gout symptoms in my feet from time to time. Also both the medications above can with certain foods make you more prone to gout symptoms. If however you did get a complete gout attack, you would not have to ask if it is the gout. The pain of a gout attack is generally off the pain scale, so much so that even the slightest touch of anything will cause pain at a high level, and you would not be able to walk. However you can experience gout symptoms that are not that bad, but are induced by your medication. You should have your doctor check your Uric Acid levels to insure you are not prone to gout problems. All it requires is a simple blood test.

Mav - Age 61

61 year old male
Posted: 2009-05-21 10:39:03     Rating: Star Star Star Star Star

Answer/Reply:

HI, I'VE BEEN ON ATENENOL FOR YEARS AND I DON'T HAVE ANY SIDE AFFECTS. I GUESS IT D DEPENDS ON YOUR BODY EVERYTHING TREATS EVERYONE DIFFERENT. CHECK WITH YOUR DOCTOR. THANKS JACKIE SHINALL 47 YR OLD FEMALE

47 year old female
Posted: 2009-06-05 10:26:56     Rating: Star Star Star Star Star

Answer/Reply:

The foot pain could be a number of things. When taking HCTZ, you should always take it with orange juice or a banana so as to keep from losing potassium. Doctors often forget to tell their patients that little bit of very useful information. When on any diuretic, potassium loss is almost inevitable if you don't increase your potassium rich foods, such as bananas, orange juice or potatoes. Potassium loss causes leg and foot cramps and pain.

41 year old female
Posted: 2009-05-21 15:49:44     Rating: Star Star Star Star Star

Answer/Reply:

The pain could be from any number of things. Doctors OFTEN forget to tell patients that when on HCTZ or any diuretic, that it is important to take them with a banana or a glass of orange juice so your potassium level doesn't decrease. Potassium loss can cause foot and leg cramps and pain.

41 year old female
Posted: 2009-05-21 15:57:09     Rating: Star Star Star Star Star

Answer/Reply:

Since taking this medication, my potassium level dropped and my doctor had to prescribe me potassium pills. My doctor re-checked it a month after he started me on the potassium pills and it is normal again. But he doesn't want to take me off the potassium pills. I sometimes have a "full" feeling around my ankles with some tenderness of the feet. I was advised to eat more citrus fruits, greens, chicken and fish.

36 year old female

35 year old female
Posted: 2009-06-03 14:13:32     Rating: Star Star Star Star Star

Answer/Reply:

I also have taken furosemide for quite a long time, and I did have a potassium problem, which my doctor prescribed potassium pills, and it improved immediately.

47 year old female
Posted: 2009-06-09 01:26:10     Rating: Star Star Star Star Star

Answer/Reply:

I have also been on this drug and have the same foot pain you described, to the point I can no longer go for my long walks anymore. Even going out to the mailbox is painful. In December diagnosed with chronic renal failure.

59 year old female

59 year old female
Posted: 2009-06-15 17:24:19     Rating: Star Star Star Star Star

Question/Comment:

Does glipizide and HCTZ have any risks taken together.

47 year old female
Posted: 2009-05-03 14:56:44     Rating: Star Star Star Star Star

Answer/Reply:

ALWAYS ASK YOUR PHARMICIST QUESTIONS LIKE THIS. PLUS IF YOU GET ALL MEDS AT THE SAME PHARMACY, THEN THEY ARE SUPPOSE TO BY LAW HAVE A COMPUTER PROGRAM THAT SHOULD RED FLAG ANY MEDS THAT DON'T GO TOGETHER OR THAT UNSAFE TOGETHER AND THEY SHOULD AUTOMATICALLY TELL YOU BY A PHONE CALL OR WHEN YOU COME TO PICK IT UP AND THEY SHOULD ALSO CALL YOUR DR. AND POINT IT OUT TO HIM AND GET HIS RECOMMENDATION FOR SOMETHING ELSE.

48 year old female
Posted: 2009-05-24 03:22:52     Rating: Star Star Star Star Star

Question/Comment:

When my doctor put me on Hydrochlorothiazide, for my blood pressure, after taking it for a week I had severe pain in my feet I couldn't walk,so I went to see him, he was shocked to see me in my condition,and he kept apologizing because he didn't tell me hydrochlorothiazide, the side effect is gout, so becareful.......

68 year old female
Posted: 2009-02-21 20:27:59     Rating: Star Star Star Star Star

Answer/Reply:

Hi, I too have taken hydrochlorothiazide and NEVER had any problems at all except once.. I had a severe infection in my great toe, which was MISDIAGNOSED as gout because of lab results when the doc (in the ER) did not take into account that I was a long-time user of a diuretic. Finally got it sorted out but not before I took medications for gout which have their own side effects. Your result from the medication happens so very seldom, it is no wonder your doctor was upset; he certainly never expected this to happen and possibly had never seen it before. This is a good medication in most circumstances. It is sad it did not do the job for you.

62 year old female
Posted: 2009-03-18 20:44:58     Rating: Star Star Star Star Star

Answer/Reply:

I have been takng Hydrochlorthiazide for 5 years to control my blood pressure. My only side effects have been a few bad cases of vertigo. However, these dizzy spells were pretty severe.

42 year old female
Posted: 2009-03-31 12:25:42     Rating: Star Star Star Star Star

Answer/Reply:

Yes, I was given the same med, hydrochorothiazide for my blood pressure. My hair was completely gone in the top of my head within six months after taking hydrochorothzide.

56 year old female

56 year old female
Posted: 2009-03-20 21:46:47     Rating: Star Star Star Star Star

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