Get Informed: Desyrel
Active Ingredient(s)
Trazodone
What does it do?
This product is used for the treatment of depression. It is believed to work affecting the activity of serotonin, an important chemical in the brain.
- Last Text Update:
- 2009-Nov-20 6:20 PM
- Last Data Update:
- 2009-Nov-20 6:52 PM
Other Names
- Trazodone
- Trazodone HCl
- Desyrel
- Trazodone Hydrochloride
How Safe Is It?
- Your Risk Rating
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- Average Risk Rating
-
- Pregnancy Category:
- C
Black Box Warning
This product has a black box warning relating to increased risk of suicidal thoughts and behavior when used in children and adolescents with depression.
Facts & Figures
- Date Approved
- 24 Dec 1981
- Est US Patients*
- 2,715,000
- Generic Available
- Yes
- OTC Available
- No
User Age Distribution*
< 21
21-39
40-59
60+
Age (Years)
* Estimated number of US people currently taking Desyrel or its active ingredient based on population adjusted patient numbers registered with iGuard.org.
Recent alerts for Desyrel
There have been no alerts regarding Desyrel during the past year.
Desyrel Safety Report
Learn more about iGuard's risk ratings
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What is Desyrel used for?
iGuard.org is currently tracking more than 15,900 patients that use Desyrel (or similar drugs with the same active ingredient(s)). Use the table below to learn why iGuard users take this product; click on any underlined condition to get information on other medications used for treatment.
| Disease / Condition | % | Average Severity |
|---|---|---|
| Insomnia | 79% | 
|
| Depression | 29% |
|
| Anxiety | 15% |
|
| Bipolar Disorder | 9% | 
|
| Sleep Apnea | 2% |
|
| Other | 10% |
|
How well does Desyrel work?
iGuard.org regularly polls our more than 15,900 users taking Desyrel (or similar drugs with the same active ingredient(s)) using the Treatment Satisfaction Questionnaire for Medications (TSQM) . This feedback is continuously updated in tables below for the benefit of the iGuard community. To request scores for specific patient subgroups, please contact research@iguard.org.
Average Satisfaction Score
(out of 10)
Average Effectiveness Score
(out of 10)
- 80%
- of patients are confident that the good things about Desyrel outweigh the bad things.
- 19%
- of patients wish they were told more before they started taking Desyrel.
Common Side Effects of Desyrel
iGuard.org regularly polls our more than 15,900 users taking Desyrel (or similar drugs with the same active ingredient(s)) to monitor the development and frequency of side-effects. This feedback is continuously updated in tables and graphs below for the benefit of the iGuard community.
41% of patients experience side-effects on Desyrel
4% of patients experience signifcant side-effects on Desyrel
Most Common Side Effects...
-
Grogginess/Confusion
-
Drowsiness
-
Dry Mouth
-
Vivid Dreams
-
Dizziness
-
Mental Haziness
-
Weight Gain
-
= 10%
Less than 1%: Anxiety, Constipation, Depression, Dryness, Elevated Heart Rate, Fatigue, Headache, Memory/Speech Problems, Muscle Pain, Nausea/Vomiting, Ringing Ears
Global Patient Feedback for Desyrel (Trazodone) ( Post a comment )
Question/Comment:
i have been on 150mg of trazodone for three days, my stool is black, is this another side affect?any help would be appriciated. williamsc535@gmail.com
50 year old Female
Posted: 2009-09-01 18:12:46
Answer/Reply:
hey look up the serotonin syndrome i think that is the side effects of that
25 year old Male
Posted: 2009-09-08 21:18:52
Answer/Reply:
No, if anything risperidone would make you constipated.
16 year old Male
Posted: 2009-11-01 13:35:28
Question/Comment:
i have been taking trazadone for 3 years it works very well for sleeplessness
41 year old Male
Posted: 2009-09-01 15:27:02
Question/Comment:
im taken trazandone and i have weight gain and trouble sleeping and i just feel like crap just about all the time
34 year old Male
Posted: 2009-08-07 11:33:02
Answer/Reply:
What do you take it for? Is it helping? I've taken it consistently for more than 6 years and for a couple of years a few years earlier. I take it for sleep and it may help some with my depression but I take 2 other medications specifically for that. I'd talk to your doctor about it.
55 year old Female
Posted: 2009-08-10 23:15:59
Answer/Reply:
I have also taken trazadone for several years, but I only take it as needed because there are some unpleasant side affects: constipation, weight gain, waking up a bit drousy. I also snore like a bear (as I've been told) when I take trazadone at night. On the positive side.... Trazadone helps ease the muscle & joint pain that I suffer from.
36 year old Female
Posted: 2009-08-19 15:43:06
Answer/Reply:
I've been on Trazadone for 24 years since a major head trauma and brain surgery. Since the surgery I've suffered with insomnia and tinnitis. My dosage is up to 300mg now. I had to go to an in-patient pain clinic and the doctors there told me that this medication helps with chronic headaches, muscle and joint pain, and also helps other meds work better. I've never thought about changing to other newer forms of anti-depressants since this one is a wonder drug for me. Before Trazadone, I was taking some others, but I found myself gaining weight because I was sleep eating. If taken daily you won't wake up groggy after about a month or if upping the dosage.
53 year old Female
Posted: 2009-09-21 12:46:50
Answer/Reply:
It does not cause weight gain. I have lost 40 pounds in the past 6 mths I have been taking it for about 4 years with no problem whatsoever.
65 year old Female
Posted: 2009-09-24 19:35:00
Question/Comment:
I have been taking Trazadone for more than a year for serotonin issues and anxiety. I have had no side effects other than weight gain. I have not had any anxiety attacks or sleeplessness since I started taking it.
37 year old Female
Posted: 2009-08-01 08:39:10
Answer/Reply:
I am currently taking 375 mg of Trazadone - I started taking it over 5 years ago. It really helps me sleep sounder and I do not wake up with that hazey feeling (well, maybe for the 1st week after up'ing my dosage).
49 year old Female
Posted: 2009-08-29 12:18:19
Question/Comment:
I have been taking 300 mg of Trazodone a day for 10 years now. I am being treated for depression, high blood pressure and bipolar disorder, with other perscriptions.** I have been having serious foot problems all of a sudden, with bad curculation and pai recently.**I don't know if anyone else has this problem. It also might be caused by all my medications mixed or because I also have a bulged disc which is damaging my back, side and leg. If someone else has these foot probblem without haveing other problems, please replay or email me at khaney46@yahoo.com. I am really conserned about all my health issues, and will be working to get them corrected soon. Thank You Ken
49 year old Male
Posted: 2009-07-26 16:22:05
Answer/Reply:
I would definately say it is from your bulged disc. I have sciatica and now I have heel spurs because I was not walking right because of the back pain. Same way, I would not say it is the medication.
22 year old Female
Posted: 2009-08-18 17:30:22
Answer/Reply:
Im not a physician, but sometimes having a thyroid problem/disease (as I am familiar with) can put someone on an emotional rollar coaster & cause a lot of nasty symptoms...
36 year old Female
Posted: 2009-08-19 15:51:14
Answer/Reply:
have you been checked for gout? some medications mixed together can cause this condition in your feet. Trazadone is one of these medications. i continue to take trazadone but changed some others. gout causes problems in the feet and ankles. check with your doctor. gout is easy to treat but very painful!
41 yr old female
42 year old Female
Posted: 2009-08-21 21:13:03
Answer/Reply:
74 year old female
I have been taking Trazadone 100 mg for at least 10 years for depression, anxiety and not being able to sleep well. I do not have any side effects and usually have no trouble sleeping.
75 year old Female
Posted: 2009-08-22 14:03:41
Answer/Reply:
I too, have been having problems with my legs and feet. I've been taking Trazodone for about three months and I notice my feet and legs (especially my left leg and foot) has been really burning. I was told that I have a low form of diabetes, but I'm not sure that is the cause of it. I also am worried about what's going on. I am now going to another doctor to see if it's my medication or the diabetes that's causing all my problems.
I wish you all the luck on your problem.
54 year old Female
Posted: 2009-08-25 22:26:03
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71
Patient Comments about
Desyrel