Get Informed: Desyrel
Active Ingredient(s)
Trazodone
What does it do?
This product is used for the treatment of depression. It is believed to work affecting the activity of serotonin, an important chemical in the brain.
- Last Text Update:
- 2010-Mar-21 2:25 AM
- Last Data Update:
- 2010-Mar-20 9:02 PM
Other Names
- Trazodone
- Trazodone HCl
- Desyrel
- Trazodone Hydrochloride
- Molipaxin
How Safe Is It?
- Your Risk Rating
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- Average Risk Rating
-
- Pregnancy Category:
- C
Black Box Warning
This product has a black box warning relating to increased risk of suicidal thoughts and behavior when used in children and adolescents with depression.
Facts & Figures
- Date Approved
- 24 Dec 1981
- Est US Patients*
- 2,640,000
- Generic Available
- Yes
- OTC Available
- No
User Age Distribution*
< 21
21-39
40-59
60+
Age (Years)
* Estimated number of US people currently taking Desyrel or its active ingredient based on population adjusted patient numbers registered with iGuard.org.
Recent alerts for Desyrel
There have been no iGuard.org alerts regarding Desyrel during the past year.
Desyrel Safety Report
Learn more about iGuard's risk ratings
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What is Desyrel used for?
iGuard is currently tracking more than 17,500 patients that use Desyrel (or similar drugs with the same active ingredient(s)). Use the table below to learn why iGuard users take this product; click on any underlined condition to get information on other medications used for treatment.
| Disease / Condition | % | Average Severity |
|---|---|---|
| Insomnia | 75% | 
|
| Depression | 39% |
|
| Anxiety | 21% |
|
| Bipolar Disorder | 14% | 
|
| Sleep Apnea | 8% |
|
| Fibromyalgia | 8% |
|
| Pain-Generalized | 5% |
|
| Neuropathic Pain | 4% |
|
| Other | 3% | 
|
How well does Desyrel work?
iGuard regularly polls our more than 17,500 users taking Desyrel (or similar drugs with the same active ingredient(s)) using the Treatment Satisfaction Questionnaire for Medications (TSQM) . This feedback is continuously updated in tables below for the benefit of the iGuard community. To request scores for specific patient subgroups, please contact research@iguard.org.
Average Satisfaction Score
(out of 10)
Average Effectiveness Score
(out of 10)
- 88%
- of patients are confident that the good things about Desyrel outweigh the bad things.
- 14%
- of patients wish they were told more before they started taking Desyrel.
Common Side Effects of Desyrel
iGuard regularly polls our more than 17,500 users taking Desyrel (or similar drugs with the same active ingredient(s)) to monitor the development and frequency of side-effects. This feedback is continuously updated in tables and graphs below for the benefit of the iGuard community.
34% of patients experience side-effects on Desyrel
5% of patients experience signifcant side-effects on Desyrel
Most Common Side Effects...
-
Grogginess/Confusion
-
Drowsiness
-
Dizziness
-
Altered Taste/Smell
-
= 10%
Less than 1%: Anxiety, Dryness, Erectile Problems, Fatigue, Headache, Increased Appetite, Memory/Speech Problems, Nausea/Vomiting, Restlessness, Vision Changes, Vivid Dreams, Weight Gain, Withdrawal Problems
Global Patient Feedback for Desyrel (Trazodone) ( Post a comment )
Question/Comment:
I have been on so many different types of anti-depressants it is scary but so far with my taking trazodone @ 100mg @ night and celexa @50mg in the morning my mood is getting somewhat better although sleeping is still a challenge at night but when you have back pain you would have a challenge sleeping also that is why I also take the over the counter pm medicine
45 year old Female – Source: iGuard United States
Posted: 2010-01-26 15:35:07
Question/Comment:
I am a 67 year old female. After months of losing weight, having constant anxiety attacks, memory problems, and feeling as if I existed in the twilight zone, and after monthly visits to my family physician because of the weight loss, I decided that perhaps the 50 mg. of Trazadone she had prescribed to me was the culprit. I started by cutting back to 25 mg. for about a week, and then simply stopped it altogether. It took about three weeks to feel like a normal person again. Making this decision to take control of my medication probably saved my life because I though about committing suicide numerous times a day the entire time I was on Trazadone, but held off taking action because I knew I could always make the decision 'tomorrow'. I'm glad I waited. I now take my 75 mcg. of the brand Levoxyl (had my physician write 'do not substitute' to see if taking the brand would help), 20 mg. of generic Enalapril and 5 mg. of generic Norvasc for high blood pressure, and 12.5 mg. Ambien CR to help me sleep. Go to http://www.aafp.org/20000301/1437.html and look at the list of drugs and their effect on older people, or query the internet for information on antidepressants or psychotropic drugs if a physician recommends them for you or your parents or relatives. It may save someone's life.
67 year old Female – Source: iGuard United States
Posted: 2010-01-15 23:43:32
Question/Comment:
Besides being slighly groggy in the morning.. Trazadone is amazing.. i suffer from very bad anxiety .. especially right before bed and this takes it right away and then knocks me out and allows me to sleep soundly.. im only prescribed 50 mgs but it still works great. Could be because im a very petite person.
25 year old Female – Source: iGuard United States
Posted: 2009-12-13 17:57:17
Question/Comment:
i take trazadone for depression 150mgs for a year now i get the groggy feeling in the morning but as i have read above it does not out me to sleep i have to take another med to put me to sleep and trazadone keeps me asleep and it does nothing for any of my pain joint or otherwise im really not sure its for me.
37 year old Female – Source: iGuard United States
Posted: 2009-11-23 17:07:52
Question/Comment:
i have been on 150mg of trazodone for three days, my stool is black, is this another side affect?any help would be appriciated. williamsc535@gmail.com
51 year old Female – Source: iGuard United States
Posted: 2009-09-01 18:12:46
Answer/Reply:
hey look up the serotonin syndrome i think that is the side effects of that
25 year old Male – Source: iGuard United States
Posted: 2009-09-08 21:18:52
Answer/Reply:
No, if anything risperidone would make you constipated.
16 year old Male – Source: iGuard United States
Posted: 2009-11-01 13:35:28
Answer/Reply:
I've been on 150-300 mg trazodone for several years. Black stool has never been a side effect. You'd best tell your doctor about this immediately.
57 year old Male – Source: iGuard United States
Posted: 2010-01-29 17:56:52
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Patient Comments about
Desyrel