Get Informed: Activella

12

Patient Comments about
Activella

Active Ingredient(s)

Activella

What does it do?

Activella

This product is used in the treatment of menopausal symptoms and to prevent bone loss in women. It has both estrogens and progesterone.

Last Text Update:
 2010-Mar-18 8:02 PM
Last Data Update:
 2010-Mar-19 9:03 PM

Other Names

  • Activella
  • Combipatch
  • Evorel Conti
  • Kliovance
  • Novofem
  • Estrapak
  • Kliofem
  • Evorel Sequi
  • Estracombi
  • Elleste-Duet Conti

How Safe Is It?

Your Risk Rating
Please log in
Average Risk Rating
0: On hold
Pregnancy Category:
N/A

Black Box Warning

This product has a black box warning relating to the increased risk of blood clots, heart attacks, breast cancer, and dementia.

Facts & Figures

Date Approved
18 Nov 1998
Est US Patients*
72,820
Generic Available
No
OTC Available
No

User Age Distribution*

0

< 21

2

21-39

71

40-59

27

60+

Age (Years)

* Estimated number of US people currently taking Activella or its active ingredient based on population adjusted patient numbers registered with iGuard.org.

Other Resources

Recent alerts for Activella

There have been no iGuard.org alerts regarding Activella during the past year.

Activella Safety Report

0: On hold

The iGuard risk rating for Activella is on hold. It means that we're waiting for more patients taking this medication to join iGuard before we can provide a more accurate safety assessment of this product.

Learn more about iGuard's risk ratings

  • Please login or register (it's free) so iGuard can check how Activella interacts with other drugs and diseases in your profile.

What is Activella used for?

iGuard is currently tracking more than 480 patients that use Activella (or similar drugs with the same active ingredient(s)). Use the table below to learn why iGuard users take this product; click on any underlined condition to get information on other medications used for treatment.

Disease / Condition % Average Severity
Menopausal Symptoms 100% 5

How well does Activella work?

iGuard regularly polls our more than 480 users taking Activella (or similar drugs with the same active ingredient(s)) using the Treatment Satisfaction Questionnaire for Medications (TSQM) . This feedback is continuously updated in tables below for the benefit of the iGuard community. To request scores for specific patient subgroups, please contact research@iguard.org.

Average Satisfaction Score

(out of 10)

Average Effectiveness Score

(out of 10)

72 76
92%
of patients are confident that the good things about Activella outweigh the bad things.
0%
of patients wish they were told more before they started taking Activella.

Common Side Effects of Activella

iGuard regularly polls our more than 480 users taking Activella (or similar drugs with the same active ingredient(s)) to monitor the development and frequency of side-effects. This feedback is continuously updated in tables and graphs below for the benefit of the iGuard community.

16%

16% of patients experience side-effects on Activella

0%

< 1% of patients experience signifcant side-effects on Activella


Most Common Side Effects...

  • 10% Mood/Behavior Changes
  • 10% Breakthrough Bleeding
  • = 10%

Global Patient Feedback for Activella ( Post a comment )

Comments, Questions, and Answers
Show Newest | Oldest first

Question/Comment:

I'm hoping to get a more definitive answer than I've been getting from my doctor (he's always vague)! Is there any accepted/standard length of time a woman should be on HRT? I've heard no more than 5 years. I've been on Activella for almost 10, and only recently (last couple of months) have I finally noticed that the hot flashes do not return when I discontinue the HRT for a while. This time it's been almost 2 months since a dose, and so far no hot flashes. Is it normal to (finally) stop the hot flashes? If so, can I safely discontinue the HRT therapy? I'm concerned about the heart-related risks if I discontinue it. I've heard that HRT helps protect the heart. I'd like to know if that's true, also. Thanks

60 year old Female – Source: iGuard United States

Posted: 2010-03-17 18:03:59

Question/Comment:

I have been on the Combipatch for 2 weeks. I am experiencing severe mood swings, sadness being the most prevalent. I am also taking Bupropion and Lorazepam for anxiety. Is the combination of these meds something to be concerned about?

58 year old Female – Source: iGuard United States

Posted: 2010-01-30 12:34:56

iGuard Answer/Reply:

The combination should be well tolerated. Any time hormones are added, there is a chance for mood swings and depression. Sometimes it can take several months to adjust to the dose. If it is unbearable, speak with your doctor and perhaps they can change you to different hormones.

Posted: 2010-02-07 21:41:26

Question/Comment:

I have already applied my second patch and am still experiencing hot flashes, I am on the lowest dose. How long should it take to relieve them. No other side effects.

55 year old Female – Source: iGuard United States

Posted: 2009-10-26 16:51:43

iGuard Answer/Reply:

Estrogen supplementation and finding the right dose is highly variable from patient to patient. Please discuss your concerns with your doctor so he can establish a baseline history for you and then continue to monitor the patch's effectiveness and make dose adjustments as necessary.

Posted: 2009-11-03 21:20:52

Question/Comment:

My patch dosage is 50/250.

54 year old Female – Source: iGuard United States

Posted: 2009-05-06 12:04:27

Answer/Reply:

GOOD TO SEE OTHERS ON PATCH !! MY DOSAGE IS 50/140. FIRST TIME USER AND I AM LOOKING FORWARD TO THIS BEING MY MIRACLE PATCH !! HOW LONG WILL I HAVE TO WAIT UNTIL I SEE SIGNS OF NO MOR HOT FLASHES AND NIGHT SWEATS ALSO DID YOU FIND THAT THIS PATCH HELPS WITH ANIEXTY?

51 year old Female – Source: iGuard United States

Posted: 2009-07-22 16:48:53

iGuard Answer/Reply:

CombiPatch will reach its steady state within 24 hours of applying your first patch. Your symptoms should start to be relieved fairly quickly after you start the medication. Hormone replacement therapy can cause emotional changes in some women. These changes can include the onset of anxiety. If you feel your anxiety is worse, make an appointment to discuss it with your doctor as quickly as possible.

Posted: 2009-08-01 00:56:09

Question/Comment:

I have been using this patch for over one year. In recent weeks, I have had severe itching, swelling, and redness at patch site. It takes a good 2-weeks before I can apply patch to same area. I will be seeing my gynecologist to discuss this matter!

60 year old Female – Source: iGuard United States

Posted: 2009-01-05 10:30:11

Answer/Reply:

I never had any problems with mine. I usually place mine in the same area, however, maybe you might wish to switch sides. I place mine on my lower abdomen (stomach), right above my thigh area. It also might be good to stay away from the area you have been placing patch when it causes all the problems mentioned above. Good luck! It sure beats the pills and any other form of "staying sane" that I have encountered through the menapause stage.

54 year old Female – Source: iGuard United States

Posted: 2009-05-06 12:09:13

Answer/Reply:

HELLO ! I AM HAPPY TO FIND SOMEONE ON THE SITE THAT HAS USED THIS PATCH . I JUST STARTED ON THE PATCH LAST NIGHT FOR THE FIRST TIME.AFTER BATTLING MENOPAUSE FOR MANY MANY YEARS . NOT KNOWING MUCH ABOUT HRT!! ONLY THE BAD NEWS ABOUT THE SIDE EFFECTS. I WENT TO A NEW OB-GYN AND SHE PLACED ME ON THE PATCH BECAUSE I DID NOT WANT TO TAKE PILLS .I HAVE A LOT OF LOWER STOMACH !! SMILE !! SO WHERE IS THE BEST PLACE TO PLACE THE PATCH ? SOME TELL ME ON THE HIP -BUTTOCK AREA !! DO YOU AGREE OR DISAGREE ? I FEEL A LITTLE LIGHT HEADED AND A MILD HEADACHE COMING ON DO YOU THINK THIS IS A SIDE EFFECT SINCE I AM JUST BEGINNING !! I AM ON A THREE MONTH TRAIL !! THANKS FOR YOU REPLY !!NOW WHERE SHOULD I PUT THE PATCH SINCE I AM OVER WEIGHT !!

51 year old Female – Source: iGuard United States

Posted: 2009-07-22 16:39:38

iGuard Answer/Reply:

The recommended placement of CombiPatch is the lower abdomen, away from the waistline and breasts. You should rotate where you place the patch and not use the same spot for at least one week. Headache is a reported side effect of hormone replacement therapy. Your headache could be a side effect of the medication, or it could just be coincidental. Light-headedness is not a reported side effect. Pay attention to your symptoms and if they continue, let your doctor know.

Posted: 2009-08-01 00:38:20

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