Get informed: Wellbutrin

Safety/Interactions Indications Side Effects
Facts & Figures Effectiveness Discussion
MEDICATION SAFETY CHECK

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The average iGuard risk rating for Wellbutrin is BLUE. It means that Wellbutrin normally has a low risk of serious or long-term side effects if used under normal medical supervision.

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Why do patients use Wellbutrin?

iGuard.org is currently tracking more than 16,940 patients that use Wellbutrin (or similar drugs with the same active ingredient(s)). Use the table below to learn why iGuard users take this product; click on any underlined condition to get information on other medications used for treatment.
DISEASE / CONDITION % AVERAGE SEVERITY
DEPRESSION
87%
ANXIETY
12%
BIPOLAR DISORDER
9%
ATTENTION DEFICIT DISORDER
<5%
SMOKING ADDICTION
<5%

How well does Wellbutrin work?

iGuard.org regularly asks patients taking Wellbutrin to provide feedback on: disease/condition treated, effectiveness/satisfaction, side effects, and information they wish they knew prior to starting the medication. This feedback is continuously updated for the benefit of other members of the iGuard community.
Average Satisfaction Score
(out of 10)
74 %
Average Effectiveness Score
(out of 10)
73 %
93%   of patients are confident that the good things about Wellbutrin outweigh the bad things.


What do iGuard.org users wish they were told before starting this product?
9%
% patients who wished they learned more before starting
9% of patients taking Wellbutrin wish they were told more about this product before they started it.

TOP THINGS PATIENTS WISHED THEY KNEW...
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ABOUT Wellbutrin
Active Drug(s): Bupropion
WHAT DOES IT DO?
This product is used in the treatment of depression, and as an aid to smoking cessation treatment. It is believed to work by acting on norepinephrine and dopamine, two important chemicals in the brain.
photo
VIEW: US Prescribing Info
VIEW: Wikipedia Content
VIEW: Patient Info Guide

HOW SAFE IS IT?
Your Risk Rating: PLEASE LOG IN
Average Risk Rating (GENERAL)
Pregnancy Category C
BLACK BOX WARNING
This product has a black box warning relating to increased risk of suicidal thoughts and behavior when used in children and adolescents with depression.


FACTS & FIGURES
Date Approved 30 Dec 1985
US Pts on Drug 2007 6,495,553
Generic Available YES
OTC Available NO


What side-effects do iGuard.org users commonly report for Wellbutrin?

33%

33% of patients experience side-effects on Wellbutrin


3%

3% of patients experience SIGNIFICANT side-effects on Wellbutrin


MOST COMMON SIDE EFFECTS...
BLURRED VISION
RESTLESSNESS
NAUSEA
SWEATING
DIZZINESS
SUICIDAL THOUGHTS
DRY MOUTH
WEIGHT GAIN
HEADACHE
COMPULSIVE BEHAVIOR
INSOMNIA
= 10%

Drug Comments for Wellbutrin (Bupropion)

Comments, Questions, and Answers Show Newest | Oldest First 

Question/Comment:

I started taking Wellbutrin, and about 18 days after starting to take it, it caused a skin reaction.
It was very itchy and raised swelling of the skin all over the body including the head. The Dr said to immediately stop taking Wellbutrin. A day after I stopped taking Wellbutrin the skin rash subsided.
Then the Pharmacist said that sometimes you can take the same medication and it might not have the same side effect, appon wich the Dr dissagreed. About six months later I started to take Wellbutrin again successfully without any side affects, and am on it now for 3,5 months now.

48 year old male
Posted: 2008-11-18 01:26:24     Rating: Star Star Star Star Star

Question/Comment:

As far as the side effect that states "weight gain" I have always heard it helps with weight loss. Is this not true, and if not can you explain why.

Thanks
Pam

49 year old female
Posted: 2008-11-11 06:53:12     Rating: Star Star Star Star Star

Answer/Reply from iGuard:

In the Wellbutrin XL prescribing information, both weight loss and increased appetite have been reported. Compared to other anti depressant medications, Wellbutrin is known to have a low risk of weight gain and sexual side effects.

Posted: 2008-11-11 08:29:10    

Question/Comment:

I am very satisfied with this product Wellbutrin. I take 150mg, once a day, usually in the mornings. I do not have alot of these side effects. I guess you have to try different brands of depressiants before you find the one that works for you,everyone is different. "I have tried many". I have noticed that if I miss a dose for a few days it changes my mood and I feel very poorly. I have not taken the name brand only the Bupropion and it works great for me so I will leave WELL enough alone. My doctor told me it takes at least 30 days before you know if it is working for you.

41 year old female
Posted: 2008-10-27 16:02:28     Rating: Star Star Star Star Star

Question/Comment:

I thought that the generic brand was a good as the REAL meds. Can someone explain the difference and why so many people have seen significant changes when they are put on the generic, and not for the better?

56 year old female
Posted: 2008-10-17 13:54:05     Rating: Star Star Star Star Star

Answer/Reply:

My Dr. explained this to me when my insurance company made me take a generic form instead of the Proventil inhaler I had used in the past. i'm offering an intelligent guess here...

When you take any med your body becomes used to that specific chemical make up of the drug. Then you then have to take the generic, the slightly different chemical make up of the drug is not recognized by your body.

This does not happen to everyone, but imagine how scary of a situation it created when having an asthma attack and the "rescue" inhaler doesn't work.

Doc told me if I had started out on the generic, it likely would have been accepted by and worked for my body. He then had to fight w/ the insurance company to make them cover the name brand. Another thing doc told me was "it is your body, you know what is going on inside of you, don't let anyone try to convince you that your are not feeling__(insert problem)___, when you know you are."

Words to live by! BUT, when I started taking the generic Wellbutrin, I had no problem what so ever. Go figure.

47 year old female
Posted: 2008-10-26 22:46:37     Rating: Star Star Star Star Star

Answer/Reply:

The generic medication may be the same as Wellbutrin but the time release capsule is not. The patent for the Wellbutrin capsule has not expired, and the generic substitue does not release the medication gradually as the Wellbutrin does. Instead, there is a surge of medication into the body followed by a lack of or shortage of medication thereafter. The most recent news release may be read in the following link. http://www.pharmalot.com/2008/09/fda-to-review-generic-wellbutrin-again/



58 year old female
Posted: 2008-11-03 15:51:55     Rating: Star Star Star Star Star

Question/Comment:

I was tapered off of Fluoxetine on to Bupropion and I've been taking 300 mg of Bupropion XL for about 6 weeks now. I have a constant feeling of dizziness and frequent headaches. I have woken up in the morning and almost fell over because I couldn't keep my balance. I got out of the shower once and went to flip my head over to put the towel on it and when I stood up I felt like I was going to black out. I had to grab hold of the sink. I find that I also feel like I will black out when I am playing sports. I often have to stop and take a breather so I don't pass out cold in the middle of the court. When I lie down for bed, I often have muscle spasms that I never had before. I feel like my appetite has returned at full force so I have naturally put on some weight. On a better note, Bupropion has given me my energy and libido back. It does not effect my sleep the way it does to others.

23 year old female
Posted: 2008-10-16 16:33:14     Rating: Star Star Star Star Star

Answer/Reply:

Sounds like you are on too high of a dose... if your doctor prescribed you for 300 mgs right off the bat, then they are the batty ones... you should slow increase this med. I was on 100 mgs of this, and I was supposed to move my dosage up, and it being too expensive for me out of pocket (after insurance paid their part) i couldnt take it anymore, and I wish i could... it was doing a world of good for me!!!

35 year old female
Posted: 2008-11-09 14:36:49     Rating: Star Star Star Star Star

Answer/Reply:

You are too young to have side effects like the ones you describe. I agree, your dosage is too high. I had similar results on the 300 mgs and suggest you go back down to 150 mgs. Perhaps your symptoms won't be as severe.

49 year old female
Posted: 2008-11-15 23:45:02     Rating: Star Star Star Star Star

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Wellbutrin can have many different drug interactions. Drug interactions of Wellbutrin can vary depending upon other drugs and conditions in your health profile. A list of common drug interactions for Wellbutrin can be found., Wellbutrin side effects include a range of different complaints. Wellbutrin has been associated with different side effects. Side effects of Wellbutrin can vary with dose. This may the only place to learn about real world side effects of Wellbutrin. Wellbutrin safety are displayed on this page