Get informed: SIMVASTATIN

Safety/Interactions Indications Side Effects
Facts & Figures Effectiveness Discussion
MEDICATION SAFETY CHECK

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The average iGuard risk rating for SIMVASTATIN is BLUE. It means that SIMVASTATIN normally has a low risk of serious or long-term side effects if used under normal medical supervision.

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Why do patients use SIMVASTATIN?

iGuard.org is currently tracking more than 13,250 patients that use SIMVASTATIN (or similar drugs with the same active ingredient(s)). Use the table below to learn why iGuard users take this product; click on any underlined condition to get information on other medications used for treatment.
DISEASE / CONDITION % AVERAGE SEVERITY
HIGH CHOLESTEROL
100%

How well does SIMVASTATIN work?

iGuard.org regularly asks patients taking SIMVASTATIN to provide feedback on: disease/condition treated, effectiveness/satisfaction, side effects, and information they wish they knew prior to starting the medication. This feedback is continuously updated for the benefit of other members of the iGuard community.
Average Satisfaction Score
(out of 10)
66 %
Average Effectiveness Score
(out of 10)
71 %
80%   of patients are confident that the good things about SIMVASTATIN outweigh the bad things.


What do iGuard.org users wish they were told before starting this product?
17%
% patients who wished they learned more before starting
17% of patients taking SIMVASTATIN wish they were told more about this product before they started it.

TOP THINGS PATIENTS WISHED THEY KNEW...
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ABOUT SIMVASTATIN
Active Drug(s): SIMVASTATIN
WHAT DOES IT DO?
This product is primarily used to reduce cholesterol. It works by blocking an important enzyme (HMG-CoA reductase) used by the body to produce cholesterol.
photo
VIEW: US Prescribing Info
VIEW: Wikipedia Content

HOW SAFE IS IT?
Your Risk Rating: PLEASE LOG IN
Average Risk Rating (GENERAL)
Pregnancy Category X
Black Box Warning No

FACTS & FIGURES
Date Approved 23 Dec 1991
US Pts on Drug 2007 8,750,543
Generic Available YES
OTC Available NO


What side-effects do iGuard.org users commonly report for SIMVASTATIN?

20%

20% of patients experience side-effects on SIMVASTATIN


4%

4% of patients experience SIGNIFICANT side-effects on SIMVASTATIN


MOST COMMON SIDE EFFECTS...
MUSCLE PAIN
MEMORY/SPEECH PROBLEMS
FATIGUE
RUNNY NOSE/CONGESTION
INSOMNIA
= 10%

Drug Comments for SIMVASTATIN (SIMVASTATIN)

Comments, Questions, and Answers Show Newest | Oldest First 

Question/Comment:

I was just switched by an internist from vytorin to simvastatin .. I cannot believe this .. I have MS and FMS .. have been struggling with IBS and now am having major blockage .. I just read this after taking my meds and am now wondering if this is what is causing my issues .. I am scared to death .. I take Alprazolam, Trazadone, Baclofen, UltramER and now I just quit smoking after 38 yrs. and thinking it could have been the Chantix did not take it, now I am not going to take the Simvastin and pray that I can get through this horrid ordeal ...

Thank you for having this site .. I just took a look here ... and am shocked ... I am going back to my Vytorin and pray that I don't need surgery for blocked intestines .. I should change my preferences so that I receive alerts ...

51 year old female
Posted: 2008-08-16 22:26:20     Rating: Star Star Star Star Star

Question/Comment:

I've been taking Zocor genaric Symvastatin for at least five years. I told the doctor pain and cramps in my legs very depressed and tired all the time. She said I have to take it. I'm low income and they won't give me any other kind. After readind your alert on my computer I have stopped. Thank you any other ideas? D G New Jersery

62 year old female
Posted: 2008-08-10 12:09:52     Rating: Star Star Star Star Star

Answer/Reply:

You stated that your doctor said "you have to take it". Absolutely not. You don't have to take it If it is making you sick. Take charge your own health. Besides, you are a female, and statin drugs have shown no reduction in mortality in females in trials. In fact the only group to benefit from statin drugs are middle aged males with cardiovascular disease, or several high risk factors. And then 100 men had to take a statin for over 3 years to prevent one cardiac event. Those are not very promising odds.

51 year old male
Posted: 2008-08-28 10:54:05     Rating: Star Star Star Star Star

Question/Comment:

Hi, I am a 55 year old female, I have been on Simvastin for years, but now with the letter I recieved today from IGUARD SAFETY ALERTS, I was shocked when I read this, especially since I not only have heart disease, I only have 1 kidney working, and it was tested May 19, 2008 and my kidney function is down to 14% , I have been having pain in muscles and I also have been dealing with pain in my chest area, my doctor had ordered a ekg and a cat scan because some symptons I have been having she thought it was TIA;s (mini strokes) So after she reviewed the test, she put me on a medication which is to help prevent a stroke from happening AGGRENOX, so when I got home, new meds in tow, I sat down and pulled the new medicene papers out the warnings & so on they give you.
Well right on page 1 is a list of things if you have do not take, it says do not take if you have kidney disease, right there in black and white, so I did not take it the first night and I placed a call to my doctor at the VA Hospital and when she returned my call, she says yes she knows your not to take if you have kidney disease, or kidney failure, but she then tells me that because of the symptons of the TIA's I had been having, she said that this AGGRENOX would possibly keep me from having a bad stroke.
So now I get the letter telling me that something else can cause kidney failure, can someone please tell me what is safe to take when you have ;1 Kidney disease/Kidney Failure 2 Heart Disease - 3 Thyroid Disease (hyper thyroidism)
I have lost the function of 1 kidney, because a Doctor that I was seeing when I was able to work( picture this: I weighed 110 pounds, and when I was seen by this doctor, my blood pressure was way out of wack, but he did not try to figure out why I had high blood pressure, all he did was kept giving me pills for high BP until he got it low enough to be safe, But because he did not try to find out why I had high BP when I begin having other problems, I lost my job, cause BP was way to high the company I worked for could not let me operate a vehicle taking clients to do the contract work they did. So after about 2 years, I am seeing the Public Health Department doctor by then, and when they done lab work I had a high # of createine level, which concerned this doctor, after several test, he sent me to have a MRI done, and when the results come back, my right kidney had shrunk so small compared to my left kidney, so he sent me to a kidney doctor which after he reviewed, he asked me why the doctors I had been seeing had not caught this, he said if they had of searched to find out why I was having BP problems they would have found out that there was a kidney problem and then they could have saved my right kidney, it had blockages so no blood flow was going thru , which is what the kidneys require to flush the kidney out.
So now , the question is WHAT PILLS should I be taking, most of the ones I am on now all 11 of them most have some type of side effect that makes me not want to take the pills, but I want to live, so I keep taking them.................. anyone have any ideal which meds would be best for me?

55 year old female
Posted: 2008-08-09 20:05:25     Rating: Star Star Star Star Star

Question/Comment:

I take simcor but it is so expensive has anyone taken the generic for this and if so how did it work?

60 year old female
Posted: 2008-07-30 12:00:23     Rating: Star Star Star Star Star

Question/Comment:

I started taking Simvastatin last fall. Since I started, I have had three episodes involving severe diarrhea, stomach cramps, and severe fatigue. I thought I had the stomach flu. I was talking with a friend today and found out she had similar experiences. Have any of you?

47 year old female
Posted: 2008-07-25 19:30:16     Rating: Star Star Star Star Star

Answer/Reply:

I have taken simvastatin for at least 5 years and have had no side effects and the results appear to be very good.

62 year old male
Posted: 2008-07-29 10:38:32     Rating: Star Star Star Star Star

Answer/Reply:

Yes! I'm 57, female. Last night I was up 4 times with severe diarrhea. The 5th time I did not wake up in time and had to shower and change my bedding in the middle of the night. Then, I was afraid to go back to sleep. Even 2 immodium during the night did not help.

This is not the first time either! I normally never have this problem, only since starting Simvastatin. I will not live like this. I'm going to stop taking them to see if it stops. I'd been taking it at bedtime as the bottle suggested. And yes, this morning I felt flu-ish but with no fever and now (tonight) I'm fine.

58 year old female
Posted: 2008-08-26 19:57:09     Rating: Star Star Star Star Star

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SIMVASTATIN can have many different drug interactions. Drug interactions of SIMVASTATIN can vary depending upon other drugs and conditions in your health profile. A list of common drug interactions for SIMVASTATIN can be found., SIMVASTATIN side effects include a range of different complaints. SIMVASTATIN has been associated with different side effects. Side effects of SIMVASTATIN can vary with dose. This may the only place to learn about real world side effects of SIMVASTATIN. SIMVASTATIN safety are displayed on this page