Get informed: Synthroid

Safety/Interactions Indications Side Effects
Facts & Figures Effectiveness Discussion
MEDICATION SAFETY CHECK

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The average iGuard risk rating for Synthroid is ORANGE mostly because Synthroid may cause serious side effects if its dose is not tightly controlled. It means that Synthroid should normally be used cautiously to minimize the risk of serious side effects.

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Why do patients use Synthroid?

iGuard.org is currently tracking more than 40,700 patients that use Synthroid (or similar drugs with the same active ingredient(s)). Use the table below to learn why iGuard users take this product; click on any underlined condition to get information on other medications used for treatment.
DISEASE / CONDITION % AVERAGE SEVERITY
HYPOTHYROIDISM
100%

How well does Synthroid work?

iGuard.org regularly asks patients taking Synthroid to provide feedback on: disease/condition treated, effectiveness/satisfaction, side effects, and information they wish they knew prior to starting the medication. This feedback is continuously updated for the benefit of other members of the iGuard community.
Average Satisfaction Score
(out of 10)
77 %
Average Effectiveness Score
(out of 10)
74 %
92%   of patients are confident that the good things about Synthroid outweigh the bad things.


What do iGuard.org users wish they were told before starting this product?
30%
% patients who wished they learned more before starting
30% of patients taking Synthroid wish they were told more about this product before they started it.

TOP THINGS PATIENTS WISHED THEY KNEW...
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ABOUT Synthroid
Active Drug(s): Levothyroxine
WHAT DOES IT DO?
This product is primarily used to treat hypothyroidism. It consists of T4, one of the important hormones produced by the thyroid gland.
photo
VIEW: US Prescribing Info
VIEW: Wikipedia Content
VIEW: Patient Info Guide

HOW SAFE IS IT?
Your Risk Rating: PLEASE LOG IN
Average Risk Rating (ELEVATED)
Pregnancy Category A
BLACK BOX WARNING
This product has a black box warning relating to its ineffectiveness and dangers as a weight loss treatment.


FACTS & FIGURES
Date Approved 1 Dec 1963
US Pts on Drug 2007 15,437,137
Generic Available YES
OTC Available NO


What side-effects do iGuard.org users commonly report for Synthroid?

15%

15% of patients experience side-effects on Synthroid


2%

2% of patients experience SIGNIFICANT side-effects on Synthroid


MOST COMMON SIDE EFFECTS...
RESTLESSNESS
HAIR LOSS
HEADACHE
FATIGUE
PALPITATIONS
BREATHLESSNESS
DRY SKIN
INSOMNIA
= 10%

Drug Comments for Synthroid (Levothyroxine)

Comments, Questions, and Answers Show Newest | Oldest First 

Question/Comment:

i have been taking levothyroxine for over a year. At first I had higher energy levels....but now my Dr said she overmedicated me and has tod me to stop the pill one day a week. I have not lost any weight and was always thin prior to the thyroid problms. I am starting to feel sluggish again. Should I ask for a change in the medication?

55 year old female
Posted: 2008-11-15 16:40:01     Rating: Star Star Star Star Star

Question/Comment:

Im on levoxyl, I had my thyroid removed Dr gave me 25mcg of the Levoxyl. I started 3 days ago. It give me an upset stoamch when taken with out food so I took it with something. I have an A1C level od 6.9 and am not on medication the medications cause me to get sick , low blood sugar and headaches . I also take meds for bp . I read here that Levoxyl has bad side efffects . Im going to ask my primary to change it . what is a better medication to take ? please help im 55 yrs old female
thank you

55 year old female
Posted: 2008-11-15 11:17:01     Rating: Star Star Star Star Star

Question/Comment:

I have been told by every pharmacist that there is a significant difference between Synthroid and generics (which is the only brand/generic I have been warned about). Also, my endo is adamant I take my Synthroid upon waking in the morning, with distilled water, and nothing else by mouth for an hour. He monitors me closely for med/blood levels (I also have diabetes 2 and take Vytorin for high cholesterol) and says my numbers are "perfect." More to the point, I feel just fine after years of up-&-down and so-so.

58 year old female
Posted: 2008-11-14 13:43:51     Rating: Star Star Star Star Star

Answer/Reply:

That is weird. I started off taking Synthroid and then I switched to the generic brand. When I was taking the real thing, I seemed to do alot better with it. Now that I'm taking the generic(levothryoxine), it seems to not do anything for me. I am tired all the time, I have gained some weight. What exactly did the pharmacist say was the difference. Just curious...

Trina

38 year old female
Posted: 2008-11-18 12:18:12     Rating: Star Star Star Star Star

Question/Comment:

I have been on Synthroid for 15 years. Last year, my doctor changed my cholesterol medication which I had to take in the morning. One year later, my thryoid hormone was out of balance. After researching both medications, I now take my cholesterol medication 2 hours AFTER I take Synthroid. Two months later, my TSH is back to normal.

47 year old female
Posted: 2008-11-14 11:04:05     Rating: Star Star Star Star Star

Question/Comment:

i take synthroid and have been taking it for years and i just don't know if it is working like it should, all i do know is that i have been diagnosed with hypothyroidism and that is why they put me on it, my mom has grave's disease and has had her thyroid shrunk with radioactive iodine twice and she is still having problems and now they say her para-thyroid is the reason. i guess what i am trying to say is she had hers shrunk and my mother-in-law had hers surgically removed and both of them still have to take the same medication as i do so what was the purpose of them having the procedures that they had done if they still have to take the medicine anyway. i know i don't have anymore energy which i thought that i would and i am still gaining weight and i just don't understand? what is the true purpose of taking this medicine? i mean nothing changes in you not in my opinion except my mood swings sometimes...

38 year old female
Posted: 2008-11-14 08:56:46     Rating: Star Star Star Star Star

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Synthroid can have many different drug interactions. Drug interactions of Synthroid can vary depending upon other drugs and conditions in your health profile. A list of common drug interactions for Synthroid can be found., Synthroid side effects include a range of different complaints. Synthroid has been associated with different side effects. Side effects of Synthroid can vary with dose. This may the only place to learn about real world side effects of Synthroid. Synthroid safety are displayed on this page