Get informed: Prempro

Safety/Interactions Indications Side Effects
Facts & Figures Effectiveness Discussion
MEDICATION SAFETY CHECK

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The iGuard risk rating for Prempro is ON HOLD. It means that we're waiting for more patients taking this medication to join iGuard before we can provide a more accurate safety assessment of this product.

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Why do patients use Prempro?

iGuard.org is currently tracking more than 1,630 patients that use Prempro (or similar drugs with the same active ingredient(s)). Use the table below to learn why iGuard users take this product; click on any underlined condition to get information on other medications used for treatment.
DISEASE / CONDITION % AVERAGE SEVERITY
MENOPAUSAL SYMPTOMS/HRT
100%

How well does Prempro work?

iGuard.org regularly asks patients taking Prempro to provide feedback on: disease/condition treated, effectiveness/satisfaction, side effects, and information they wish they knew prior to starting the medication. This feedback is continuously updated for the benefit of other members of the iGuard community.
Average Satisfaction Score
(out of 10)
74 %
Average Effectiveness Score
(out of 10)
77 %
96%   of patients are confident that the good things about Prempro outweigh the bad things.


What do iGuard.org users wish they were told before starting this product?
26%
% patients who wished they learned more before starting
26% of patients taking Prempro wish they were told more about this product before they started it.

TOP THINGS PATIENTS WISHED THEY KNEW...
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ABOUT Prempro
Active Drug(s): Estrogens Conjugated with Medroxyprogest Acetate
WHAT DOES IT DO?
This product is used primarily for oral contraception. It contains the progestin (medroxyprogesterone) and estrogens.
photo
VIEW: US Prescribing Info
VIEW: Wikipedia Content

HOW SAFE IS IT?
Your Risk Rating: PLEASE LOG IN
Average Risk Rating (ON HOLD)
Pregnancy Category X
BLACK BOX WARNING
This product has a black box warning relating to the increased risk of blood clots, heart attacks, breast cancer, and dementia.


FACTS & FIGURES
Date Approved 30 Dec 1994
US Pts on Drug 2007 720,867
Generic Available NO
OTC Available NO


What side-effects do iGuard.org users commonly report for Prempro?

20%

20% of patients experience side-effects on Prempro


0%

< 1% of patients experience SIGNIFICANT side-effects on Prempro


MOST COMMON SIDE EFFECTS...
WEIGHT GAIN
SWEATING
COLD FINGERS/TOES
DRY SKIN
= 10%

Drug Comments for Prempro (Estrogens Conjugated with Medroxyprogest Acetate)

Comments, Questions, and Answers Show Newest | Oldest First 

Question/Comment:

I have been on this medication for a little over a month now and the main issue or side-effect that I have relates to my breasts. My breasts are extremely sore. My breast are not extremely large; I wear a 36B bra, however, I find that the only way I can relieve some of the tenderness is to wear a bra at all times; even while sleeping. Is this something most other women experience while taking this drug, and if so, is there anything, aside from not taking the medication, that can relieve this symptom?

52 year old female
Posted: 2008-11-11 17:28:36     Rating: Star Star Star Star Star

Question/Comment:

I have been taking Prempro for less than a month. I am about on day 14. I feel as if a menstral cycle has started this week with bleeding and cramps. Should I continue to take Prempro or stop through this period? I went a whole year without a period last year but had one menstral period4 months ago.
49 year old female

49 year old female
Posted: 2008-08-30 07:32:19     Rating: Star Star Star Star Star

Answer/Reply:

The best thing to do would be to discuss this with your doctor. However, if I recall correctly, during my earlier stages of menopause, and when I first started to use Prempro, I had some spotting and cramps on occasion. Eventually it they went away, completely. Having said this, I still say it’s best to speak with your doctor about this. You just never know from one person to the next what such symptoms might mean.

52 year old female
Posted: 2008-11-11 17:34:23     Rating: Star Star Star Star Star

Answer/Reply:

That happen to me I called my Doctor and he put me on the lowest dose which is 0.3/1.5MG EZ-DL

53 year old female
Posted: 2008-12-18 17:16:55     Rating: Star Star Star Star Star

Question/Comment:

I am 49 years old and have been taking Prempro for several months. It has help so much with menopausal syptoms. I was very pleased with it until I found out about the increased chance of getting dementia. My Grandmother had dementia and my Mother does, so this really scares me. Any advice? (I have had problems with depression and anxiety all my life. I am on medication for these too.)

49 year old female
Posted: 2008-08-17 21:01:34     Rating: Star Star Star Star Star

Question/Comment:

I am pleased with Prempro

66 year old female
Posted: 2008-03-10 00:00:00     Rating: Star Star Star Star Star

Question/Comment:

as long as you have no preexisting conditions that can be affected by Prempro I see no reason not to take it

58 year old female
Posted: 2008-03-10 00:00:00     Rating: Star Star Star Star Star

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Prempro can have many different drug interactions. Drug interactions of Prempro can vary depending upon other drugs and conditions in your health profile. A list of common drug interactions for Prempro can be found., Prempro side effects include a range of different complaints. Prempro has been associated with different side effects. Side effects of Prempro can vary with dose. This may the only place to learn about real world side effects of Prempro. Prempro safety are displayed on this page