Get informed: Premarin

Safety/Interactions Indications Side Effects
Facts & Figures Effectiveness Discussion
MEDICATION SAFETY CHECK

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The average iGuard risk rating for Premarin is ORANGE mostly because Premarin has been associated with an increased risk of cancer, as well as heart, clot and memory problems. It means that Premarin should normally be used cautiously to minimize the risk of serious side effects.

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Why do patients use Premarin?

iGuard.org is currently tracking more than 7,880 patients that use Premarin (or similar drugs with the same active ingredient(s)). Use the table below to learn why iGuard users take this product; click on any underlined condition to get information on other medications used for treatment.
DISEASE / CONDITION % AVERAGE SEVERITY
MENOPAUSAL SYMPTOMS/HRT
97%
OSTEOPOROSIS
<5%

How well does Premarin work?

iGuard.org regularly asks patients taking Premarin to provide feedback on: disease/condition treated, effectiveness/satisfaction, side effects, and information they wish they knew prior to starting the medication. This feedback is continuously updated for the benefit of other members of the iGuard community.
Average Satisfaction Score
(out of 10)
72 %
Average Effectiveness Score
(out of 10)
71 %
91%   of patients are confident that the good things about Premarin outweigh the bad things.


What do iGuard.org users wish they were told before starting this product?
5%
% patients who wished they learned more before starting
5% of patients taking Premarin wish they were told more about this product before they started it.

TOP THINGS PATIENTS WISHED THEY KNEW...
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ABOUT Premarin
Active Drug(s): Estrogens Conjugated
WHAT DOES IT DO?
This product is primarily used in the treatment of menopause symptoms and prevention of bone density loss. It is synthetic hormone replacement.
photo
VIEW: US Prescribing Info
VIEW: Wikipedia Content

HOW SAFE IS IT?
Your Risk Rating: PLEASE LOG IN
Average Risk Rating (ELEVATED)
Pregnancy Category X
BLACK BOX WARNING
This product has a black box warning relating to increased risk of endometrial cancers and an increased risk of blood clots, heart attacks, invasive breast cancer, and dementia.


FACTS & FIGURES
Date Approved 8 May 1942
US Pts on Drug 2007 3,354,109
Generic Available NO
OTC Available NO


What side-effects do iGuard.org users commonly report for Premarin?

6%

6% of patients experience side-effects on Premarin


2%

2% of patients experience SIGNIFICANT side-effects on Premarin


MOST COMMON SIDE EFFECTS...
HEADACHE
NAUSEA
= 10%

Drug Comments for Premarin (Estrogens Conjugated)

Comments, Questions, and Answers Show Newest | Oldest First 

Question/Comment:

i am a 69 year old women and have been taking premarin since i was 46..i have had no negative symptoms..my skin is good as well as strong bones..i do take progesterone every three months for 14 days to balance out the premarin..

68 year old female
Posted: 2009-01-06 10:35:37     Rating: Star Star Star Star Star

Question/Comment:

i am a 69 year old women and have been on premarin since i was 46 years old..i Ihave never had any of the negative symtoms discribed..my skin and bones as well a general well being are great..although i do take progesterine for 14 days every 3 months to balance..

68 year old female
Posted: 2009-01-06 10:26:01     Rating: Star Star Star Star Star

Question/Comment:

I HAVE BEEN TAKING PREMERIN FOR ABOUT 48 YEARS. HAVE NEVER HAD ANY PROBLEMS AT ALL ONLY WHEN THE DR. WANTED TOOK MEOFF OF IT. I GOT THE HOT FLASHES BACK AND SEEMED TO GET QUITE IRRATABLE SO I WAS TOLD. AM NOW ON THE LOWEST DOSAGE AND HAVE ALWAYS TAKEN IT EVEY DAY AND WILL FOR THE REST OF MY LIFE. MY UROGLOGIST ALSO GAVE ME THE VAGINAL CREAM..HOWEVER ONLY USE IT SPASMODICALLY, BUT IS A GREAT AID..
78 YR.OLD FEMALE

57 year old female
Posted: 2009-01-05 17:47:02     Rating: Star Star Star Star Star

Question/Comment:

I have taken Premarin for 20 years. After my partial hysterectomy. To me its a wonder drug.
No more hot flashes. I sleep good at night,and my bone scan is good.I also have a
mammogram every year. I feel great.

60 year old female

66 year old male
Posted: 2009-01-02 20:04:03     Rating: Star Star Star Star Star

Question/Comment:

I had my hysterectomy in 2004... been on and off the premarin, more often off because I do not suffer the hot flashes or other menopausal symptoms, Premarin makes me have severe adult acne which I get fed up with and quit taking it... only thing about the premarin I do like is I have problems with vaginal dryness and stress incontinence, Premarin does help with those two things!

35 year old female
Posted: 2008-12-31 17:46:41     Rating: Star Star Star Star Star

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Premarin can have many different drug interactions. Drug interactions of Premarin can vary depending upon other drugs and conditions in your health profile. A list of common drug interactions for Premarin can be found., Premarin side effects include a range of different complaints. Premarin has been associated with different side effects. Side effects of Premarin can vary with dose. This may the only place to learn about real world side effects of Premarin. Premarin safety are displayed on this page