Get informed: Estradiol

Safety/Interactions Indications Side Effects
Facts & Figures Effectiveness Discussion
MEDICATION SAFETY CHECK

rating icon
The average iGuard risk rating for Estradiol is BLUE. It means that Estradiol normally has a low risk of serious or long-term side effects if used under normal medical supervision.

To learn more about iGuard's risk ratings, click here.

!Please login or register (it's free) so iGuard can check how Estradiol interacts with other drugs and diseases in your profile.

Why do patients use Estradiol?

iGuard.org is currently tracking more than 5,300 patients that use Estradiol (or similar drugs with the same active ingredient(s)). Use the table below to learn why iGuard users take this product; click on any underlined condition to get information on other medications used for treatment.
DISEASE / CONDITION % AVERAGE SEVERITY
MENOPAUSAL SYMPTOMS/HRT
100%

How well does Estradiol work?

iGuard.org regularly asks patients taking Estradiol to provide feedback on: disease/condition treated, effectiveness/satisfaction, side effects, and information they wish they knew prior to starting the medication. This feedback is continuously updated for the benefit of other members of the iGuard community.
Average Satisfaction Score
(out of 10)
78 %
Average Effectiveness Score
(out of 10)
77 %
84%   of patients are confident that the good things about Estradiol outweigh the bad things.


What do iGuard.org users wish they were told before starting this product?
12%
% patients who wished they learned more before starting
12% of patients taking Estradiol wish they were told more about this product before they started it.

TOP THINGS PATIENTS WISHED THEY KNEW...
Don't miss out!
Please log in, or register (its FREE) to view the top responses of iGuard.org users
Click here to get your free, personal
medication safety report - checking
for drug interactions and
other problems.

ABOUT Estradiol
Active Drug(s): Estradiol
WHAT DOES IT DO?
This product is commonly used in the treatment of menopausal symptoms, as well as for the prevention of osteoporosis and topical treatment of vulvar atrophy. It supplements the body's production of estrogen hormone.
photo
VIEW: US Prescribing Info
VIEW: Wikipedia Content

HOW SAFE IS IT?
Your Risk Rating: PLEASE LOG IN
Average Risk Rating (GENERAL)
Pregnancy Category X
BLACK BOX WARNING
This product has a black box warning relating to its increased risk of endometrial cancer and cardiovascular problems.


FACTS & FIGURES
Date Approved 15 Jul 1954
US Pts on Drug 2007 3,498,795
Generic Available YES
OTC Available NO


What side-effects do iGuard.org users commonly report for Estradiol?

13%

13% of patients experience side-effects on Estradiol


0%

< 1% of patients experience SIGNIFICANT side-effects on Estradiol


MOST COMMON SIDE EFFECTS...
ITCH
WEIGHT GAIN
FLUID RETENTION/SWELLING
VAGINAL DISCHARGE
= 10%

Drug Comments for Estradiol (Estradiol)

Comments, Questions, and Answers Show Newest | Oldest First 

Question/Comment:

After hot sweats and irregular menstruation i discovered that i have fibroids and that i'm menoausal so i had an hysterectomy with both ovaries removed in June 2008. I started using oestrodode gel 1g/day plus decalcit (for the next 5 years according to my doctor). No more sweats i feel normal but i'm concerned about gaining weight. what can you recommend? what is the percentage of having breast cancer on the long term

44 year old female
Posted: 2008-12-03 09:32:29     Rating: Star Star Star Star Star

Question/Comment:

I am a 16 year old female that was diagnosed with P.C.O.S. (Poly Cistic Ovarian Syndrome) and my estrogen levels are about 12 and 14 instead of between 100 and 250. My doctor put me on Estrogel recently to help raise my levels because an estrogen patch and birth control have done nothing. It basically made me go crazy. I gained 6 lbs. in one night and I could not connect my thoughts with my words. I had really bad, blurry vision and people kept asking me if I was drugged. I had DRASTIC mood swings and could not even recognize I was having them. I HATED this product. I don't know if it just had to do with my young age, but I have never had such severe reactions for such a constant period of time (one week) with a medicine. It was extremely icky.

16 year old female
Posted: 2008-11-02 16:40:58     Rating: Star Star Star Star Star

Question/Comment:

I had a complete hysterectomy at 29 after unsuccessfully trying every other method to get my endo under control. 18 years later, I do not regret the choice to go on HRT and will continue to take it as long as I can stick that little patch on! I agree...don't listen to what your neighbors, friends or family say! Make an educated decision for yourself. When my mother developed Stage 3 breast cancer at age 64, I did the research all over again and sought the advice from a hormone specialist. After careful consideration, I opted to try and lower my dose from the 1mg patch to the .05. It was a bit rough for a month or so, but my body adapted and I feel I made the "right choice" for me. I'm proud to say that Mom is a five year survivor and so even if I do get it, I know I can be treated. My quality of life is as important to me in my late forties as it was in my late twenties. I've been able to keep my weight steady with a healthy diet and moderate exercise, so I'm an advocate of HRT without reservation!

47 year old female
Posted: 2008-10-30 16:12:01     Rating: Star Star Star Star Star

Question/Comment:

I am a 60 year old female who had a hysterectomy when I was 21. I have been on hormones ever since, either Premarin or Estradiol. I only had side effects in the beginning, when the doctors were trying to adjust to the proper dosage for me. Since that time, I have maintained quite well with no side effects. I only have side effects, like sweats, etc. when I do not take the medication.
I am in good health with arteries, etc. all in good shape.

60 year old female

60 year old female
Posted: 2008-09-25 21:42:47     Rating: Star Star Star Star Star

Answer/Reply:

I had a hysterectomy when I was 35 and was put on estradiol immediately after that. I am now 38 years old and I have had no menopause symptons (night sweats and etc.) since I have been taking the estradiol. I am pleased with the results of estradiol. But recently I switched to a different doctor and he seems to think I should try to get off of my estradiol. I really don't want to and I just called my previous doctor to make an appointment to see him about this. So I was just wondering what you would suggest I do?

37 year old female
Posted: 2008-12-01 15:40:39     Rating: Star Star Star Star Star

Question/Comment:

I was told that I had fibroids and had to have an hysterectomy at age 28, with both ovaries being left. Within a couple of years they quit producing properly, just enough to remind me that I did have somewhat of a cycle (tender breasts, monthly water retention). Four years after the hysterectomy I was put on Premarin. At that point it was $2 a month, as of this year the insurance wants to charge $80 for three months - couldn't afford that. Estradiol is $4 a month. So asked the pharmacist and doctor about the differences of estradiol. Both said estradiol would take a bit of adjustment for my body as it was a more 'natural' estrogen versus a 'conjugated' estrogen. So far, it is working well. Have gained about 10 pounds that I am working to take back off. But have had problems with weight gain on Premarin too. As long as I take the pill every night, I 'stay under the porch & don't come out to bite' too often.

So far no osteoporosis - do have mild osteoarthritis due to an old injury, do have asthma, IBS and GERD, migraines; have had two MI's due to arterial spasm - after the second MI had a heart cath they said the arteries were clear as an 18 year old's. No blood clots.

I stay as busy as I was in my 20-30's, active at church (pastor's wife), active in clubs and community, play piano, drive handicapped son to jobs, etc.

52 year old female
Posted: 2008-09-24 18:32:09     Rating: Star Star Star Star Star

Return to main drug page         Page 1 of 8     1  2  3  4  5  6  7  8 

You may post comments for the benefit of other patients or post questions other patients might be able to answer. Comments are submitted for possible publication on the condition that they may be edited. Only your age and gender will be published with your comment, although your other user details will be securely recorded for verification purposes.

Comments may be either questions or answers to previously posted questions. Any iGuard.org user may post questions and reply.

 
Your Comments or Questions:

Simply type the text you wish to publish and click submit. Please confine comments to those that may be useful to other patients.

Max 500 characters.


 

Estradiol can have many different drug interactions. Drug interactions of Estradiol can vary depending upon other drugs and conditions in your health profile. A list of common drug interactions for Estradiol can be found., Estradiol side effects include a range of different complaints. Estradiol has been associated with different side effects. Side effects of Estradiol can vary with dose. This may the only place to learn about real world side effects of Estradiol. Estradiol safety are displayed on this page